Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025469356> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2025469356 abstract "Cell culture using bioreactors is a vital part of Cellular and Tissue Engineering. Bioreactor design continues to advance, in order to allow control over physical and chemical parameters as well as continuous assessment of cell behaviour, gene expression, and tissue formation and growth. Measurement or monitoring of many such parameters or features can be achieved with optical techniques. The current aim of cell culture is to re-create <i>in vivo</i> conditions and in order to achieve this control of the chemical environment is required and some cell types must be subjected to shear stress and/or axial loads. For creating tissue engineered cartilage chondrocytes are cultured within a biodegradable scaffold. Influences of cyclic loading and of oxygen supply on phenotype are studied. Vascular endothelial cells are subjected to fluid shear stress and the influence on prostacyclin production is measured. Optical interrogation of culture fluid, attached cells, cells in suspension and tissue constructs is carried out using a combination of spectrophotometry, analysis of scattering, and chemical sensing. Insertion of sensing probes within the culture vessel presents problems of protein adsorption to sensing surfaces. Approaches based on cell membrane mimicry are being evaluated for their potential to overcome this problem. Sensors based on immobilised fluorophores and chromaphores within either wall-mounted membranes or within optical fibres are assessed. Culture fluid turbidity is evaluated with scattering determinations and circulating glucose concentration is measured spectrophotometrically. Formed tissue is interrogated with NIR radiation and in the future will include the use of OCT." @default.
- W2025469356 created "2016-06-24" @default.
- W2025469356 creator A5027677720 @default.
- W2025469356 date "2005-01-18" @default.
- W2025469356 modified "2023-09-26" @default.
- W2025469356 title "Optical examination of cell culture in bioreactors creating simulated in vivo conditions" @default.
- W2025469356 doi "https://doi.org/10.1117/12.606170" @default.
- W2025469356 hasPublicationYear "2005" @default.
- W2025469356 type Work @default.
- W2025469356 sameAs 2025469356 @default.
- W2025469356 citedByCount "1" @default.
- W2025469356 crossrefType "proceedings-article" @default.
- W2025469356 hasAuthorship W2025469356A5027677720 @default.
- W2025469356 hasConcept C12554922 @default.
- W2025469356 hasConcept C136229726 @default.
- W2025469356 hasConcept C1491633281 @default.
- W2025469356 hasConcept C150903083 @default.
- W2025469356 hasConcept C159985019 @default.
- W2025469356 hasConcept C168170006 @default.
- W2025469356 hasConcept C176999471 @default.
- W2025469356 hasConcept C178790620 @default.
- W2025469356 hasConcept C185592680 @default.
- W2025469356 hasConcept C192562407 @default.
- W2025469356 hasConcept C202751555 @default.
- W2025469356 hasConcept C207001950 @default.
- W2025469356 hasConcept C21141959 @default.
- W2025469356 hasConcept C41625074 @default.
- W2025469356 hasConcept C49892992 @default.
- W2025469356 hasConcept C54355233 @default.
- W2025469356 hasConcept C55493867 @default.
- W2025469356 hasConcept C71924100 @default.
- W2025469356 hasConcept C81885089 @default.
- W2025469356 hasConcept C86803240 @default.
- W2025469356 hasConcept C90703135 @default.
- W2025469356 hasConceptScore W2025469356C12554922 @default.
- W2025469356 hasConceptScore W2025469356C136229726 @default.
- W2025469356 hasConceptScore W2025469356C1491633281 @default.
- W2025469356 hasConceptScore W2025469356C150903083 @default.
- W2025469356 hasConceptScore W2025469356C159985019 @default.
- W2025469356 hasConceptScore W2025469356C168170006 @default.
- W2025469356 hasConceptScore W2025469356C176999471 @default.
- W2025469356 hasConceptScore W2025469356C178790620 @default.
- W2025469356 hasConceptScore W2025469356C185592680 @default.
- W2025469356 hasConceptScore W2025469356C192562407 @default.
- W2025469356 hasConceptScore W2025469356C202751555 @default.
- W2025469356 hasConceptScore W2025469356C207001950 @default.
- W2025469356 hasConceptScore W2025469356C21141959 @default.
- W2025469356 hasConceptScore W2025469356C41625074 @default.
- W2025469356 hasConceptScore W2025469356C49892992 @default.
- W2025469356 hasConceptScore W2025469356C54355233 @default.
- W2025469356 hasConceptScore W2025469356C55493867 @default.
- W2025469356 hasConceptScore W2025469356C71924100 @default.
- W2025469356 hasConceptScore W2025469356C81885089 @default.
- W2025469356 hasConceptScore W2025469356C86803240 @default.
- W2025469356 hasConceptScore W2025469356C90703135 @default.
- W2025469356 hasLocation W20254693561 @default.
- W2025469356 hasOpenAccess W2025469356 @default.
- W2025469356 hasPrimaryLocation W20254693561 @default.
- W2025469356 hasRelatedWork W1863869726 @default.
- W2025469356 hasRelatedWork W2010358431 @default.
- W2025469356 hasRelatedWork W2047595024 @default.
- W2025469356 hasRelatedWork W2081600769 @default.
- W2025469356 hasRelatedWork W2106773990 @default.
- W2025469356 hasRelatedWork W2280310635 @default.
- W2025469356 hasRelatedWork W2358108696 @default.
- W2025469356 hasRelatedWork W2632199388 @default.
- W2025469356 hasRelatedWork W2924675638 @default.
- W2025469356 hasRelatedWork W4253886253 @default.
- W2025469356 isParatext "false" @default.
- W2025469356 isRetracted "false" @default.
- W2025469356 magId "2025469356" @default.
- W2025469356 workType "article" @default.