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• W2025483357 abstract "Objective – We estimated the prevalence and incidence of multiple sclerosis (MS) in central Finland up to 2000. Rates were compared with those in other areas in Finland. Material and method – MS cases were identified in the hospital registry by ICD codes for demyelinating diseases from 1979 to 2000. Cases with definite MS were included. Incidence and prevalence were calculated with 95% CI and standardization was performed using direct method. Results – In 1993 prevalence was 59/105 (n = 153). Incidence in 1979–93 was 3.8/105 person-years (n = 126). Rates are similar to average in areas with known rates of MS in Finland but substantially less than the over twofold MS risk in the neighbouring district Seinäjoki. Extended follow-up to 2000 in central Finland showed increasing prevalence up to 105/105 (n = 277) and a significant increase in incidence 1994–98 up to 9.2/105 (n = 105). At the same time the diagnostic use of MRI increased up to 97%. Conclusion – Central Finland represents an average risk area of MS when compared with other areas of Finland but still a high risk in global comparison. The recent rapid increase in both prevalence and incidence is largely accounted for by increased use of MRI." @default.
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• W2025483357 date "2004-11-01" @default.
• W2025483357 modified "2023-10-17" @default.
• W2025483357 title "Occurrence of multiple sclerosis in central Finland: a regional and temporal comparison during 30 years" @default.
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• W2025483357 doi "https://doi.org/10.1111/j.1600-0404.2004.00326.x" @default.
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