FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025489036> ?p ?o ?g. }

• W2025489036 endingPage "875" @default.
• W2025489036 startingPage "873" @default.
• W2025489036 abstract "The adenosine deaminase inhibitor deoxycoformycin was used in low doses to treat 19 patients with clinically aggressive T cell malignancy with a mature membrane phenotype. The patients comprised eight with prolymphocytic leukaemia, two with chronic lymphocytic leukaemia, four with adult T cell leukaemia-lymphoma, three with Sézary syndrome, and two with T cell lymphoma. Two thirds of the patients had been resistant or minimally responsive to combination chemotherapy. Complete remission was obtained in five patients (two with prolymphocytic leukaemia and one each with chronic lymphocytic leukaemia, adult T cell leukaemia-lymphoma, and Sézary syndrome) and partial remission in two others. Unmaintained complete remission lasting more than one year was seen in three patients. Responses were obtained only in patients with CD4+,CD8-membrane markers (seven out of 10), and no responses were recorded in any of the nine patients with a different phenotype. In this series remission appeared to correlate with the membrane phenotype of the neoplastic cell and not with the cytopathological diagnosis. Future studies should establish the biochemical basis for the greater sensitivity of CD4+ lymphoid cells to deoxycoformycin." @default.
• W2025489036 created "2016-06-24" @default.
• W2025489036 creator A5002670375 @default.
• W2025489036 creator A5016870972 @default.
• W2025489036 creator A5019104633 @default.
• W2025489036 creator A5047718791 @default.
• W2025489036 creator A5051208373 @default.
• W2025489036 creator A5057297204 @default.
• W2025489036 creator A5059536209 @default.
• W2025489036 creator A5061926072 @default.
• W2025489036 creator A5074074257 @default.
• W2025489036 creator A5081033062 @default.
• W2025489036 date "1987-10-10" @default.
• W2025489036 modified "2023-10-13" @default.
• W2025489036 title "Membrane phenotype and response to deoxycoformycin in mature T cell malignancies." @default.
• W2025489036 cites W2048712328 @default.
• W2025489036 cites W2062483465 @default.
• W2025489036 cites W2086984633 @default.
• W2025489036 cites W2167299711 @default.
• W2025489036 cites W2169050730 @default.
• W2025489036 cites W2325115734 @default.
• W2025489036 cites W2335457765 @default.
• W2025489036 cites W2419326912 @default.
• W2025489036 doi "https://doi.org/10.1136/bmj.295.6603.873" @default.
• W2025489036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1247926" @default.
• W2025489036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2890401" @default.
• W2025489036 hasPublicationYear "1987" @default.
• W2025489036 type Work @default.
• W2025489036 sameAs 2025489036 @default.
• W2025489036 citedByCount "16" @default.
• W2025489036 crossrefType "journal-article" @default.
• W2025489036 hasAuthorship W2025489036A5002670375 @default.
• W2025489036 hasAuthorship W2025489036A5016870972 @default.
• W2025489036 hasAuthorship W2025489036A5019104633 @default.
• W2025489036 hasAuthorship W2025489036A5047718791 @default.
• W2025489036 hasAuthorship W2025489036A5051208373 @default.
• W2025489036 hasAuthorship W2025489036A5057297204 @default.
• W2025489036 hasAuthorship W2025489036A5059536209 @default.
• W2025489036 hasAuthorship W2025489036A5061926072 @default.
• W2025489036 hasAuthorship W2025489036A5074074257 @default.
• W2025489036 hasAuthorship W2025489036A5081033062 @default.
• W2025489036 hasBestOaLocation W20254890361 @default.
• W2025489036 hasConcept C126322002 @default.
• W2025489036 hasConcept C142724271 @default.
• W2025489036 hasConcept C147483822 @default.
• W2025489036 hasConcept C167672396 @default.
• W2025489036 hasConcept C203014093 @default.
• W2025489036 hasConcept C2775952470 @default.
• W2025489036 hasConcept C2775983024 @default.
• W2025489036 hasConcept C2776991684 @default.
• W2025489036 hasConcept C2777938653 @default.
• W2025489036 hasConcept C2778461978 @default.
• W2025489036 hasConcept C2779338263 @default.
• W2025489036 hasConcept C2779399171 @default.
• W2025489036 hasConcept C2780483514 @default.
• W2025489036 hasConcept C2780653079 @default.
• W2025489036 hasConcept C2910277799 @default.
• W2025489036 hasConcept C34628245 @default.
• W2025489036 hasConcept C71924100 @default.
• W2025489036 hasConcept C90924648 @default.
• W2025489036 hasConceptScore W2025489036C126322002 @default.
• W2025489036 hasConceptScore W2025489036C142724271 @default.
• W2025489036 hasConceptScore W2025489036C147483822 @default.
• W2025489036 hasConceptScore W2025489036C167672396 @default.
• W2025489036 hasConceptScore W2025489036C203014093 @default.
• W2025489036 hasConceptScore W2025489036C2775952470 @default.
• W2025489036 hasConceptScore W2025489036C2775983024 @default.
• W2025489036 hasConceptScore W2025489036C2776991684 @default.
• W2025489036 hasConceptScore W2025489036C2777938653 @default.
• W2025489036 hasConceptScore W2025489036C2778461978 @default.
• W2025489036 hasConceptScore W2025489036C2779338263 @default.
• W2025489036 hasConceptScore W2025489036C2779399171 @default.
• W2025489036 hasConceptScore W2025489036C2780483514 @default.
• W2025489036 hasConceptScore W2025489036C2780653079 @default.
• W2025489036 hasConceptScore W2025489036C2910277799 @default.
• W2025489036 hasConceptScore W2025489036C34628245 @default.
• W2025489036 hasConceptScore W2025489036C71924100 @default.
• W2025489036 hasConceptScore W2025489036C90924648 @default.
• W2025489036 hasIssue "6603" @default.
• W2025489036 hasLocation W20254890361 @default.
• W2025489036 hasLocation W20254890362 @default.
• W2025489036 hasLocation W20254890363 @default.
• W2025489036 hasLocation W20254890364 @default.
• W2025489036 hasOpenAccess W2025489036 @default.
• W2025489036 hasPrimaryLocation W20254890361 @default.
• W2025489036 hasRelatedWork W2015931113 @default.
• W2025489036 hasRelatedWork W2024446142 @default.
• W2025489036 hasRelatedWork W2097778142 @default.
• W2025489036 hasRelatedWork W2267793562 @default.
• W2025489036 hasRelatedWork W2324875094 @default.
• W2025489036 hasRelatedWork W2409015263 @default.
• W2025489036 hasRelatedWork W2411136163 @default.
• W2025489036 hasRelatedWork W2418031697 @default.
• W2025489036 hasRelatedWork W2427404340 @default.
• W2025489036 hasRelatedWork W2129354111 @default.
• W2025489036 hasVolume "295" @default.
• W2025489036 isParatext "false" @default.
• W2025489036 isRetracted "false" @default.

• next