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• W2025527424 abstract "We demonstrate the use of an ultra-high-speed swept-source optical coherence tomography (OCT) to achieve optical micro-angiography (OMAG) of microcirculatory tissue beds in vivo. The system is based on a 1310-nm Fourier domain mode-locking (FDML) laser with 1.6-MHz A-line rate, providing a frame rate of 3.415&#xA0;KHz, an axial resolution of &#x223C;10&#x2009;&#x2009;&#x3BC;m and signal to noise ratio of 102&#xA0;dB. Motion from blood flow causes change in OCT signals between consecutive B-frames acquired at the same location. Intensity-based inter-frame subtraction algorithm is applied to extract blood flow from tissue background without any motion correction. We demonstrate the capability of this 1.6-MHz OCT system for 4D OMAG of in vivo tissue at a volume rate of 4.7 volumes/s (volume size: 512&#xD7;200&#xD7;720 voxels)." @default.
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• W2025527424 date "2015-04-09" @default.
• W2025527424 modified "2023-09-24" @default.
• W2025527424 title "4D optical coherence tomography-based micro-angiography achieved by 16-MHz FDML swept source" @default.
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• W2025527424 doi "https://doi.org/10.1364/ol.40.001779" @default.
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