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- W2025554396 abstract "Iodine-131 (I-131) whole-body scan (WBS) plays an important role in the management of patients with differentiated thyroid carcinoma (DTC), to detect normal thyroid remnants and recurrent or metastatic disease. A focus of I-131 accumulation outside the thyroid bed and the areas of physiological uptake is strongly suggestive of a distant functioning metastasis. However, many false-positive I-131 WBS findings have been reported in the literature.We describe a series of 11 personal cases of patients with DTC, collected from 1992 to 2011, in whom diagnostic or post-treatment WBS showed false-positive retention of I-131 in various locations.False-positive accumulations of I-131 on WBS may be classified according to the underlying pathophysiological mechanisms: external and internal contaminations by body secretions, ectopic normal thyroid and gastric tissues, inflammatory and infectious diseases, benign and malignant tumors, cysts and effusions of serous cavities, thymic uptake, and other non classified causes.Clinicians must be aware of possible false-positive findings to avoid misinterpretations of the I-131 WBS, which could lead to inappropriate treatments.La scintigraphie corps entier à l’Iode 131 (SCE I-131) est un examen clé dans la prise en charge des patients présentant un carcinome différencié de la thyroïde (CDT), pour identifier les résidus thyroïdiens normaux et les métastases. La fixation d’Iode 131 en dehors du lit thyroïdien et des aires de fixation physiologique suggère fortement l’existence de métastases à distance. Cependant, de nombreux faux positifs ont été rapportés dans la littérature.Nous rapportons ici 11 cas de patients avec CDT, identifiés entre 1992 et 2011, chez lesquels la SCE I-131 diagnostique ou post-thérapeutique a montré une fixation faussement positive d’Iode 131 dans différentes localisations.Les faux positifs sur la SCE I-131 peuvent être classés en fonction des mécanismes responsables : contamination interne ou externe par des sécrétions physiologiques, ectopie de tissus thyroïdien ou gastrique normaux, inflammation et causes infectieuses, tumeurs bénignes ou malignes, kystes et épanchements dans les cavités séreuses, fixation thymique et autres causes non classées.Les cliniciens doivent être avertis de la possibilité de faux positifs pour éviter des interprétations erronées de la SCE I-131, qui pourraient conduire à prescrire des traitements inappropriés." @default.
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- W2025554396 date "2013-07-01" @default.
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- W2025554396 title "Hypoglycaemia in adults: When should it be raised? How can hypoglycaemia be confirmed in non-diabetic adults?" @default.
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- W2025554396 doi "https://doi.org/10.1016/j.ando.2013.05.002" @default.
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