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- W2025561667 abstract "We report the syntheses of two pyrrolizidine alkaloid (PA) analogues (1 and 2) which exploit the novel substrate-protein coupling reagents 4 and 5. Analogues 1 and 2 incorporate the targeted PA substructural unit (i.e., a macrocyclic diester of retronecine), posses a handle for protein conjugation, and potentially maintain the conformational integrity of macrocyclic PAs." @default.
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- W2025561667 date "1992-02-01" @default.
- W2025561667 modified "2023-10-16" @default.
- W2025561667 title "Trifunctional reagents for substrate-protein conjugation: application to pyrrolizidine alkaloid analogues." @default.
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- W2025561667 doi "https://doi.org/10.1016/s0040-4020(01)92230-6" @default.
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