Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025570010> ?p ?o ?g. }
- W2025570010 endingPage "605" @default.
- W2025570010 startingPage "579" @default.
- W2025570010 abstract "Electroretinography (ERG) is a non-invasive method that can contribute to a description of the functional organization of the human retina under normal and pathological circumstances. The physiological and pathophysiological processes leading to an ERG signal can be better understood when the cellular origins of the ERG are identified. The ERG signal recorded at the cornea is initiated by light absorption in the photoreceptors which leads to activity in the photoreceptors and in their post-receptoral pathways. Light absorption in distinct photoreceptor types may lead to different ERG responses caused either by differences between the photoreceptors or between their post-receptoral pathways. The description of contributions of the different photoreceptor types to the ERG may therefore give more detailed insight in the origins of the ERG. Such a description can be obtained by isolating the responses of a single photoreceptor type. Nowadays, careful control of differently colored light sources together with the relatively well-known cone and rod fundamentals enables a precise description and control of photoreceptor excitation. Theoretically, any desired combination of photoreceptor excitation modulation can be achieved, including conditions in which the activity in only one photoreceptor type is modulated (silent substitution). In this manner the response of one photoreceptor type is isolated without changing the state of adaptation. This stimulus technique has been used to study the contribution of signals originating in the different photoreceptor types to the human ERG. Furthermore, by stimulating two or more photoreceptor types simultaneously, the interaction between the different signals can be studied. With these new techniques results of measurements in healthy subjects and patients with retinal diseases can be compared. This approach should ultimately help to develop better diagnostic tools and result in a fuller description of the changes and the pathophysiological mechanisms in retinal disorder. Finally, data obtained with cone and rod specific stimuli may lead to a reinterpretation of the standard ERG used in a clinical setting." @default.
- W2025570010 created "2016-06-24" @default.
- W2025570010 creator A5014017566 @default.
- W2025570010 date "2003-09-01" @default.
- W2025570010 modified "2023-10-15" @default.
- W2025570010 title "The assessment of L- and M-cone specific electroretinographical signals in the normal and abnormal human retina" @default.
- W2025570010 cites W120302910 @default.
- W2025570010 cites W150003809 @default.
- W2025570010 cites W1526637642 @default.
- W2025570010 cites W1541257104 @default.
- W2025570010 cites W1581147702 @default.
- W2025570010 cites W1964281102 @default.
- W2025570010 cites W1965426608 @default.
- W2025570010 cites W1967326917 @default.
- W2025570010 cites W1968222117 @default.
- W2025570010 cites W1968404921 @default.
- W2025570010 cites W1969905745 @default.
- W2025570010 cites W1970525754 @default.
- W2025570010 cites W1975149236 @default.
- W2025570010 cites W1975703312 @default.
- W2025570010 cites W1976130337 @default.
- W2025570010 cites W1976976418 @default.
- W2025570010 cites W1977097752 @default.
- W2025570010 cites W1978145999 @default.
- W2025570010 cites W1978592940 @default.
- W2025570010 cites W1979505626 @default.
- W2025570010 cites W1979909201 @default.
- W2025570010 cites W1981791555 @default.
- W2025570010 cites W1985391355 @default.
- W2025570010 cites W1988764661 @default.
- W2025570010 cites W1989746623 @default.
- W2025570010 cites W1990076689 @default.
- W2025570010 cites W1990506297 @default.
- W2025570010 cites W1991544676 @default.
- W2025570010 cites W1993687596 @default.
- W2025570010 cites W1995519869 @default.
- W2025570010 cites W1996067503 @default.
- W2025570010 cites W1996673168 @default.
- W2025570010 cites W1996813207 @default.
- W2025570010 cites W2002275859 @default.
- W2025570010 cites W2011917623 @default.
- W2025570010 cites W2018733483 @default.
- W2025570010 cites W2018975596 @default.
- W2025570010 cites W2019875735 @default.
- W2025570010 cites W2020638136 @default.
- W2025570010 cites W2021303671 @default.
- W2025570010 cites W2023102683 @default.
- W2025570010 cites W2027169123 @default.
- W2025570010 cites W2027618931 @default.
- W2025570010 cites W2030407532 @default.
- W2025570010 cites W2033485407 @default.
- W2025570010 cites W2035564375 @default.
- W2025570010 cites W2037786034 @default.
- W2025570010 cites W2037959347 @default.
- W2025570010 cites W2041279683 @default.
- W2025570010 cites W2046176884 @default.
- W2025570010 cites W2048140541 @default.
- W2025570010 cites W2052020648 @default.
- W2025570010 cites W2052916080 @default.
- W2025570010 cites W2055630468 @default.
- W2025570010 cites W2056005104 @default.
- W2025570010 cites W2056841914 @default.
- W2025570010 cites W2058646412 @default.
- W2025570010 cites W2059099814 @default.
- W2025570010 cites W2059486345 @default.
- W2025570010 cites W2060596623 @default.
- W2025570010 cites W2060962055 @default.
- W2025570010 cites W2061679633 @default.
- W2025570010 cites W2074285947 @default.
- W2025570010 cites W2075455091 @default.
- W2025570010 cites W2077628300 @default.
- W2025570010 cites W2077678003 @default.
- W2025570010 cites W2078256122 @default.
- W2025570010 cites W2079669146 @default.
- W2025570010 cites W2080127857 @default.
- W2025570010 cites W2082796628 @default.
- W2025570010 cites W2082870508 @default.
- W2025570010 cites W2083680241 @default.
- W2025570010 cites W2084213415 @default.
- W2025570010 cites W2085917210 @default.
- W2025570010 cites W2091516658 @default.
- W2025570010 cites W2098555483 @default.
- W2025570010 cites W2102006912 @default.
- W2025570010 cites W2104936947 @default.
- W2025570010 cites W2105409224 @default.
- W2025570010 cites W2109159638 @default.
- W2025570010 cites W2113660996 @default.
- W2025570010 cites W2116199444 @default.
- W2025570010 cites W2116648972 @default.
- W2025570010 cites W2117317981 @default.
- W2025570010 cites W2136719823 @default.
- W2025570010 cites W2136964897 @default.
- W2025570010 cites W2139707479 @default.
- W2025570010 cites W2152408168 @default.
- W2025570010 cites W2153053400 @default.
- W2025570010 cites W2155170674 @default.
- W2025570010 cites W2160399117 @default.
- W2025570010 cites W2161268928 @default.