FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025610939> ?p ?o ?g. }

• W2025610939 endingPage "433" @default.
• W2025610939 startingPage "426" @default.
• W2025610939 abstract "There is considerable interest in the development and evaluation of approaches for the safety assessment of novel foods, and in particular in methods for characterisation of allergenic potential. One strategy that has found favour is a tiered approach in which the potential of novel proteins to induce allergic sensitisation is assessed based on considerations of stability of the protein in a simulated gastric juice and homology with, or structural similarity to, known allergens. Linked to such an approach may be evaluation of serological identity with proteins known to cause allergic disease. With the aim of supplementing such approaches with a more direct measurement of potential allergenic activity, attempts have been made to characterise the quality of immune responses elicited in BALB/c strain mice. Such evaluations comprise measurement of IgG and IgE antibody production and (to a lesser extent) of induced cytokine expression patterns. Investigations to date suggest that in mice proteins provoke variable immune responses, those with the potential to cause allergic sensitisation stimulating IgE (and IgG) antibody production. In contrast, non-allergenic, but nevertheless immunogenic, proteins are associated with IgG antibody responses in the absence of marked IgE production. Consistent with the selective activation of selective type 2 T lymphocyte responses, exposure of mice to allergenic protein is associated with preferential expression of IL-4, -5, -10 and -13. Collectively these data suggest that characterisation of the nature of immune response induced in mice by proteins may provide a useful adjunct or alternative to current strategies for the assessment of allergenic potential." @default.
• W2025610939 created "2016-06-24" @default.
• W2025610939 creator A5014674327 @default.
• W2025610939 creator A5039090860 @default.
• W2025610939 date "2005-11-01" @default.
• W2025610939 modified "2023-10-16" @default.
• W2025610939 title "Characterisation of immune responses to food allergens in mice" @default.
• W2025610939 cites W1486761971 @default.
• W2025610939 cites W1521242203 @default.
• W2025610939 cites W1546288178 @default.
• W2025610939 cites W1596243988 @default.
• W2025610939 cites W1926875153 @default.
• W2025610939 cites W1942668068 @default.
• W2025610939 cites W1971212907 @default.
• W2025610939 cites W1972922050 @default.
• W2025610939 cites W1974078294 @default.
• W2025610939 cites W1977124528 @default.
• W2025610939 cites W1980903421 @default.
• W2025610939 cites W1982405838 @default.
• W2025610939 cites W1983749274 @default.
• W2025610939 cites W1986746242 @default.
• W2025610939 cites W1990258895 @default.
• W2025610939 cites W1994751194 @default.
• W2025610939 cites W1994931380 @default.
• W2025610939 cites W1996161052 @default.
• W2025610939 cites W2009530296 @default.
• W2025610939 cites W2011539262 @default.
• W2025610939 cites W2011807810 @default.
• W2025610939 cites W2016703714 @default.
• W2025610939 cites W2016932936 @default.
• W2025610939 cites W2023217390 @default.
• W2025610939 cites W2027914102 @default.
• W2025610939 cites W2028031129 @default.
• W2025610939 cites W2028438227 @default.
• W2025610939 cites W2030014527 @default.
• W2025610939 cites W2031232005 @default.
• W2025610939 cites W2031347383 @default.
• W2025610939 cites W2040338604 @default.
• W2025610939 cites W2047172713 @default.
• W2025610939 cites W2058951284 @default.
• W2025610939 cites W2062919446 @default.
• W2025610939 cites W2071244293 @default.
• W2025610939 cites W2071855110 @default.
• W2025610939 cites W2079636951 @default.
• W2025610939 cites W2082911677 @default.
• W2025610939 cites W2085519582 @default.
• W2025610939 cites W2091882145 @default.
• W2025610939 cites W2094312065 @default.
• W2025610939 cites W2100183318 @default.
• W2025610939 cites W2105596726 @default.
• W2025610939 cites W2111876811 @default.
• W2025610939 cites W2112376262 @default.
• W2025610939 cites W2127011470 @default.
• W2025610939 cites W2127042440 @default.
• W2025610939 cites W2135034393 @default.
• W2025610939 cites W2153592178 @default.
• W2025610939 cites W2155899124 @default.
• W2025610939 cites W4211004188 @default.
• W2025610939 cites W4211047695 @default.
• W2025610939 cites W4239393922 @default.
• W2025610939 cites W4247781632 @default.
• W2025610939 cites W4253220851 @default.
• W2025610939 doi "https://doi.org/10.1079/pns2005456" @default.
• W2025610939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16313684" @default.
• W2025610939 hasPublicationYear "2005" @default.
• W2025610939 type Work @default.
• W2025610939 sameAs 2025610939 @default.
• W2025610939 citedByCount "15" @default.
• W2025610939 countsByYear W20256109392012 @default.
• W2025610939 countsByYear W20256109392013 @default.
• W2025610939 countsByYear W20256109392014 @default.
• W2025610939 countsByYear W20256109392016 @default.
• W2025610939 countsByYear W20256109392017 @default.
• W2025610939 countsByYear W20256109392018 @default.
• W2025610939 countsByYear W20256109392019 @default.
• W2025610939 countsByYear W20256109392023 @default.
• W2025610939 crossrefType "journal-article" @default.
• W2025610939 hasAuthorship W2025610939A5014674327 @default.
• W2025610939 hasAuthorship W2025610939A5039090860 @default.
• W2025610939 hasBestOaLocation W20256109391 @default.
• W2025610939 hasConcept C141105273 @default.
• W2025610939 hasConcept C147483822 @default.
• W2025610939 hasConcept C159654299 @default.
• W2025610939 hasConcept C203014093 @default.
• W2025610939 hasConcept C207480886 @default.
• W2025610939 hasConcept C2776027960 @default.
• W2025610939 hasConcept C2776953665 @default.
• W2025610939 hasConcept C2778690821 @default.
• W2025610939 hasConcept C45189115 @default.
• W2025610939 hasConcept C86803240 @default.
• W2025610939 hasConcept C8891405 @default.
• W2025610939 hasConceptScore W2025610939C141105273 @default.
• W2025610939 hasConceptScore W2025610939C147483822 @default.
• W2025610939 hasConceptScore W2025610939C159654299 @default.
• W2025610939 hasConceptScore W2025610939C203014093 @default.
• W2025610939 hasConceptScore W2025610939C207480886 @default.
• W2025610939 hasConceptScore W2025610939C2776027960 @default.
• W2025610939 hasConceptScore W2025610939C2776953665 @default.

• next