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- W2025617846 abstract "AbstractWe immunized 63 renal transplant patients and 8 control subjects with a pneumococcal vaccine containing 14 capsular polysaccharides. The antibody levels to 12 of these polysaccharides were determined by a radioimmunoassay technique. The control subjects had antibody levels determined prior to and after immunization. The patients were divided into three groups on the basis of their underlying renal disease—Group 1, those with glomerulonephritis; Group 2, those with pyelonephritis; and Group 3, those with other renal diseases. Twenty-four Group 1, 9 Group 2, and 18 Group 3 patients had antibody levels determined before, 1 month and 1 year after immunization. The overall immune response of the patients 1 month after vaccination was not significantly different from that of the control subjects. The geometric mean antibody level at 1 year had declined by 13.8, 37.1, and 32.7% from the 1-month level for Groups 1, 2, and 3, respectively. An increasing dose of azathioprine resulted in a decreasing antibod..." @default.
- W2025617846 created "2016-06-24" @default.
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- W2025617846 date "1981-05-01" @default.
- W2025617846 modified "2023-09-26" @default.
- W2025617846 title "Humoral Immune Response of Kidney Transplant Recipients to Pneumococcal Vaccine" @default.
- W2025617846 doi "https://doi.org/10.3181/00379727-167-41126" @default.
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