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- W2025631034 abstract "The high specificity of α‐conotoxins for different neuronal nicotinic acetylcholine receptors makes them important probes for dissecting receptor subtype selectivity. New sequences continue to expand the diversity and utility of the pool of available α‐conotoxins. Their identification and characterization depend on a suite of techniques with increasing emphasis on mass spectrometry and microscale chromatography, which have benefited from recent advances in resolution and capability. Rigorous physico‐chemical analysis together with synthetic peptide chemistry is a prerequisite for detailed conformational analysis and to provide sufficient quantities of α‐conotoxins for activity assessment and structure–activity relationship studies." @default.
- W2025631034 created "2016-06-24" @default.
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- W2025631034 date "2004-06-01" @default.
- W2025631034 modified "2023-10-17" @default.
- W2025631034 title "Physico-chemical characterization and synthesis of neuronally active alpha-conotoxins" @default.
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- W2025631034 doi "https://doi.org/10.1111/j.1432-1033.2004.04146.x" @default.
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