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• W2025642271 abstract "From an information processing perspective, memories need to be acquired, encoded, stored, maintained and retrieved. As time passes after training, memories become less easily retrieved, but also become progressively more stable in the face of experimental perturbations. This process is referred to as consolidation. But the term has been used to describe two different biological processes whose relationship is poorly understood [1,2]. The first, which we refer to as biochemical consolidation, involves cell-signaling events within a neuron. The second, which we call systems consolidation, involves ongoing communication between brain regions or cell types. Although systems consolidation was first thought to be at play only in complex brains, a number of recent studies reveal its importance in Drosophila. The ease of cell type specific genetic manipulations in flies provides a unique opportunity to forge an integrated mechanistic understanding of biochemical and systems consolidation." @default.
• W2025642271 created "2016-06-24" @default.
• W2025642271 creator A5066735375 @default.
• W2025642271 creator A5068314316 @default.
• W2025642271 date "2013-02-01" @default.
• W2025642271 modified "2023-10-13" @default.
• W2025642271 title "Systems memory consolidation in Drosophila" @default.
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• W2025642271 doi "https://doi.org/10.1016/j.conb.2012.09.006" @default.
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