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• W2025642274 abstract "Positron emission tomography with [ 68 Ga]ethylenediaminetetraacetic acid ([ 68 Ga]EDTA) was used to examine the integrity of the blood–brain barrier (BBB) in five patients with dementia of the Alzheimer type and in five healthy age-matched controls. Within a scanning time of 90 min, there was no evidence that measurable intravascular tracer entered the brain in either the dementia or the control group. An upper limit for the cerebrovascular permeability–surface area product of [ 68 Ga]EDTA was estimated as 2 × 10 −6 S −1 in both groups. The results provide no evidence for breakdown of the BBB in patients with dementia of the Alzheimer type." @default.
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• W2025642274 date "1987-02-01" @default.
• W2025642274 modified "2023-09-27" @default.
• W2025642274 title "Examination of Blood — Brain Barrier Permeability in Dementia of the Alzheimer Type with [⁶⁸Ga]EDTA and Positron Emission Tomography" @default.
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• W2025642274 doi "https://doi.org/10.1038/jcbfm.1987.1" @default.
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