Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025646049> ?p ?o ?g. }
- W2025646049 endingPage "93" @default.
- W2025646049 startingPage "83" @default.
- W2025646049 abstract "Microcirculation (2010) 17, 1–11. doi: 10.1111/j.1549-8719.2009.00005.x We tested the hypothesis that segmental differences in the responsiveness and time course of vasodilation to metabolic signals putatively involved in rapid onset vasodilation (ROV) at the start of exercise exist within the skeletal muscle vasculature. Cannulated first-order (1As) and third-order arterioles (3As) of the rat gastrocnemius (G) muscle were exposed to cumulative doses of KCl, acetylcholine (Ach), or adenosine (Ado). In addition, time course and magnitude of vasodilation to localized application of these agonists were determined. 1As and 3As dilated similarly to incremental doses of the agonists. Continuous monitoring of internal diameter revealed a fast and transient dilatory response to microinjections of the agonists, with an average time delay (TD) before the onset of vasodilation of 2.8 ± 0.2 seconds (1As: 3.0 ± 0.3 seconds and 3As: 2.6 ± 0.3 seconds) and time-to-peak (TP) of 8.2 ± 0.7 seconds (1As: 10.3 ± 1 seconds and 3As:5.7 ± 0.5 seconds). No significant differences were detected for all parameters between 1As and 3As for KCl or Ado application, while 1As had a significantly longer TP and greater peak dilation than 3As to Ach. These findings demonstrate that 1As and 3As from the rat G muscle appear to have similar responsiveness to vasoactive agonists. Furthermore, the average TD before vasodilation supports a role for metabolic signals as contributors to the ROV." @default.
- W2025646049 created "2016-06-24" @default.
- W2025646049 creator A5019063151 @default.
- W2025646049 creator A5026362341 @default.
- W2025646049 creator A5037673510 @default.
- W2025646049 date "2010-02-01" @default.
- W2025646049 modified "2023-10-15" @default.
- W2025646049 title "Rapid Vasodilation in Isolated Skeletal Muscle Arterioles: Impact of Branch Order" @default.
- W2025646049 cites W1481946212 @default.
- W2025646049 cites W1519538616 @default.
- W2025646049 cites W1579794304 @default.
- W2025646049 cites W1603440370 @default.
- W2025646049 cites W1843190467 @default.
- W2025646049 cites W188099180 @default.
- W2025646049 cites W1969362766 @default.
- W2025646049 cites W1991193348 @default.
- W2025646049 cites W2000473573 @default.
- W2025646049 cites W2004860317 @default.
- W2025646049 cites W2009372606 @default.
- W2025646049 cites W2024613307 @default.
- W2025646049 cites W2033639816 @default.
- W2025646049 cites W2068807903 @default.
- W2025646049 cites W2079733002 @default.
- W2025646049 cites W2079815764 @default.
- W2025646049 cites W2090749125 @default.
- W2025646049 cites W2092928881 @default.
- W2025646049 cites W2103266410 @default.
- W2025646049 cites W2112596605 @default.
- W2025646049 cites W2115218292 @default.
- W2025646049 cites W2125205060 @default.
- W2025646049 cites W2129689780 @default.
- W2025646049 cites W2130993987 @default.
- W2025646049 cites W2139081852 @default.
- W2025646049 cites W2142430710 @default.
- W2025646049 cites W2143897682 @default.
- W2025646049 cites W2144107055 @default.
- W2025646049 cites W2150497579 @default.
- W2025646049 cites W2158917424 @default.
- W2025646049 cites W2160150028 @default.
- W2025646049 cites W2163692652 @default.
- W2025646049 cites W2183899409 @default.
- W2025646049 cites W2256366012 @default.
- W2025646049 cites W2336291503 @default.
- W2025646049 cites W4211014693 @default.
- W2025646049 cites W4252289678 @default.
- W2025646049 doi "https://doi.org/10.1111/j.1549-8719.2009.00005.x" @default.
- W2025646049 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2943204" @default.
- W2025646049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20163535" @default.
- W2025646049 hasPublicationYear "2010" @default.
- W2025646049 type Work @default.
- W2025646049 sameAs 2025646049 @default.
- W2025646049 citedByCount "26" @default.
- W2025646049 countsByYear W20256460492012 @default.
- W2025646049 countsByYear W20256460492013 @default.
- W2025646049 countsByYear W20256460492014 @default.
- W2025646049 countsByYear W20256460492015 @default.
- W2025646049 countsByYear W20256460492016 @default.
- W2025646049 countsByYear W20256460492017 @default.
- W2025646049 countsByYear W20256460492018 @default.
- W2025646049 countsByYear W20256460492022 @default.
- W2025646049 crossrefType "journal-article" @default.
- W2025646049 hasAuthorship W2025646049A5019063151 @default.
- W2025646049 hasAuthorship W2025646049A5026362341 @default.
- W2025646049 hasAuthorship W2025646049A5037673510 @default.
- W2025646049 hasBestOaLocation W20256460492 @default.
- W2025646049 hasConcept C105702510 @default.
- W2025646049 hasConcept C120770815 @default.
- W2025646049 hasConcept C126322002 @default.
- W2025646049 hasConcept C12722491 @default.
- W2025646049 hasConcept C134018914 @default.
- W2025646049 hasConcept C185592680 @default.
- W2025646049 hasConcept C2775910092 @default.
- W2025646049 hasConcept C2776991684 @default.
- W2025646049 hasConcept C2779959927 @default.
- W2025646049 hasConcept C71924100 @default.
- W2025646049 hasConceptScore W2025646049C105702510 @default.
- W2025646049 hasConceptScore W2025646049C120770815 @default.
- W2025646049 hasConceptScore W2025646049C126322002 @default.
- W2025646049 hasConceptScore W2025646049C12722491 @default.
- W2025646049 hasConceptScore W2025646049C134018914 @default.
- W2025646049 hasConceptScore W2025646049C185592680 @default.
- W2025646049 hasConceptScore W2025646049C2775910092 @default.
- W2025646049 hasConceptScore W2025646049C2776991684 @default.
- W2025646049 hasConceptScore W2025646049C2779959927 @default.
- W2025646049 hasConceptScore W2025646049C71924100 @default.
- W2025646049 hasIssue "2" @default.
- W2025646049 hasLocation W20256460491 @default.
- W2025646049 hasLocation W20256460492 @default.
- W2025646049 hasLocation W20256460493 @default.
- W2025646049 hasLocation W20256460494 @default.
- W2025646049 hasOpenAccess W2025646049 @default.
- W2025646049 hasPrimaryLocation W20256460491 @default.
- W2025646049 hasRelatedWork W1983913976 @default.
- W2025646049 hasRelatedWork W2068041289 @default.
- W2025646049 hasRelatedWork W2122344654 @default.
- W2025646049 hasRelatedWork W2154070542 @default.
- W2025646049 hasRelatedWork W2292266770 @default.
- W2025646049 hasRelatedWork W2357188473 @default.