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- W2025652804 abstract "Abstract It has been found that pretreatment of native calf thymus DNA with DNase I enables this material to serve as a “primer” in two enzyme systems for DNA synthesis in vitro , an effect which previously had been observed only when DNase was present during the course of the polymerization. This observation has led to the conclusion that DNase I probably does not play a role in DNA replication in vivo . Its action in vitro is thought to show that the polymerizing enzymes can produce fragments of DNA molecules, using molecular fragments of DNA as primers. In the course of this work some physical properties as well as the priming activity of a heattreated, reisolated DNA from calf thymus have been studied." @default.
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- W2025652804 date "1961-05-01" @default.
- W2025652804 modified "2023-09-24" @default.
- W2025652804 title "The priming activities of deoxyribonuclease-treated deoxyribonucleic acid preparations in two enzyme systems for deoxyribonucleic acid synthesis in vitro" @default.
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- W2025652804 doi "https://doi.org/10.1016/0003-9861(61)90273-9" @default.
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