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- W2025653927 abstract "A new polyvinyl chloride container plasticized with tri(2-ethylhexyl) trimellitate (PL 1240 plastic) was evaluated for use in extended platelet storage. Six leukocyte-rich platelet concentrates (mean, 0.6 × 109 white cells per bag; range, 0.3 to 1.0 × 109 per container) were prepared by removing as much of the platelet-rich plasma from blood as possible. The cells were stored at 22°C on an end-over- end agitator. An average of 1.04 ± 0.19 × 1011 platelets was recovered, and the mean pH dropped from 7.23 on day 0 to 6.68 by day 5. At the completion of the storage period. PO2 averaged 80 torr, PCO2 was 35 torr, bicarbonate concentration was 0.5 mM, and lactate concentration 29.5 mM. Thirty-one additional units of platelet concentrates, not deliberately prepared to be leukocyte-rich, on day 5 had a pH of 6.75 ± 0.39 (mean platelet yield, 0.97 ± 0.21 × 1011; PO2 and PCO2 averaged 50 and 48 torr, respectively). Following storage, the cells had an average phase microscopic morphology score of 244 (n = 17). Platelets appeared to be preserved well throughout storage when assessed by transmission and scanning electron microscopy. We conclude that platelets can be stored for 5 days in PL 1240 plastic containers with good preservation of pH and cell ultrastructure." @default.
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- W2025653927 date "1985-05-01" @default.
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- W2025653927 title "Extended storage of platelets in a new plastic container. I. Biochemical and morphologic changes" @default.
- W2025653927 doi "https://doi.org/10.1046/j.1537-2995.1985.25385219898.x" @default.
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