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- W2025665097 abstract "Small molecules that increase the cellular level of melanin can be used to study melanogenesis, and have therapeutic potential for melanin-related diseases such as albinism. We describe the identification of a potent activator of melanogenesis from a targeted combinatorial library. Treating melanocytes with our most active molecule results in a 1.8-fold increase in melanin levels, and an increase in tyrosinase-catalyzed oxidation of L-tyrosine, a key step in melanin biosynthesis." @default.
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- W2025665097 date "2009-09-28" @default.
- W2025665097 modified "2023-09-30" @default.
- W2025665097 title "A Potent Activator of Melanogenesis Identified from Small-Molecule Screening" @default.
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- W2025665097 doi "https://doi.org/10.1002/cmdc.200900194" @default.
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