Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025677386> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2025677386 endingPage "786" @default.
- W2025677386 startingPage "779" @default.
- W2025677386 abstract "There is no accepted way of measuring prothrombin time without time loss for patients undergoing major surgery who are at risk of intraoperative dilution and consumption coagulopathy due to bleeding and volume replacement with crystalloids or colloids. Decisions to transfuse fresh frozen plasma and procoagulatory drugs have to rely on clinical judgment in these situations. Point-of-care devices are considerably faster than the standard laboratory methods. In this study we assessed the accuracy of a Point-of-care (PoC) device measuring prothrombin time compared to the standard laboratory method. Patients undergoing major surgery and intensive care unit patients were included. PoC prothrombin time was measured by CoaguChek XS Plus (Roche Diagnostics, Switzerland). PoC and reference tests were performed independently and interpreted under blinded conditions. Using a cut-off prothrombin time of 50%, we calculated diagnostic accuracy measures, plotted a receiver operating characteristic (ROC) curve and tested for equivalence between the two methods. PoC sensitivity and specificity were 95% (95% CI 77%, 100%) and 95% (95% CI 91%, 98%) respectively. The negative likelihood ratio was 0.05 (95% CI 0.01, 0.32). The positive likelihood ratio was 19.57 (95% CI 10.62, 36.06). The area under the ROC curve was 0.988. Equivalence between the two methods was confirmed. CoaguChek XS Plus is a rapid and highly accurate test compared with the reference test. These findings suggest that PoC testing will be useful for monitoring intraoperative prothrombin time when coagulopathy is suspected. It could lead to a more rational use of expensive and limited blood bank resources." @default.
- W2025677386 created "2016-06-24" @default.
- W2025677386 creator A5010517239 @default.
- W2025677386 creator A5011260014 @default.
- W2025677386 creator A5012751492 @default.
- W2025677386 creator A5029350788 @default.
- W2025677386 creator A5040618445 @default.
- W2025677386 creator A5052465499 @default.
- W2025677386 creator A5082614259 @default.
- W2025677386 creator A5083254254 @default.
- W2025677386 date "2009-01-01" @default.
- W2025677386 modified "2023-09-27" @default.
- W2025677386 title "Is perioperative point-of-care prothrombin time testing accurate compared to the standard laboratory test?" @default.
- W2025677386 cites W2141531831 @default.
- W2025677386 doi "https://doi.org/10.1160/th09-03-0157" @default.
- W2025677386 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19806266" @default.
- W2025677386 hasPublicationYear "2009" @default.
- W2025677386 type Work @default.
- W2025677386 sameAs 2025677386 @default.
- W2025677386 citedByCount "15" @default.
- W2025677386 countsByYear W20256773862012 @default.
- W2025677386 countsByYear W20256773862013 @default.
- W2025677386 countsByYear W20256773862014 @default.
- W2025677386 countsByYear W20256773862015 @default.
- W2025677386 countsByYear W20256773862016 @default.
- W2025677386 countsByYear W20256773862019 @default.
- W2025677386 crossrefType "journal-article" @default.
- W2025677386 hasAuthorship W2025677386A5010517239 @default.
- W2025677386 hasAuthorship W2025677386A5011260014 @default.
- W2025677386 hasAuthorship W2025677386A5012751492 @default.
- W2025677386 hasAuthorship W2025677386A5029350788 @default.
- W2025677386 hasAuthorship W2025677386A5040618445 @default.
- W2025677386 hasAuthorship W2025677386A5052465499 @default.
- W2025677386 hasAuthorship W2025677386A5082614259 @default.
- W2025677386 hasAuthorship W2025677386A5083254254 @default.
- W2025677386 hasConcept C126322002 @default.
- W2025677386 hasConcept C141071460 @default.
- W2025677386 hasConcept C142724271 @default.
- W2025677386 hasConcept C2776376669 @default.
- W2025677386 hasConcept C2778261982 @default.
- W2025677386 hasConcept C2778382381 @default.
- W2025677386 hasConcept C2779936836 @default.
- W2025677386 hasConcept C2780434524 @default.
- W2025677386 hasConcept C31174226 @default.
- W2025677386 hasConcept C40993552 @default.
- W2025677386 hasConcept C51915194 @default.
- W2025677386 hasConcept C58471807 @default.
- W2025677386 hasConcept C64841741 @default.
- W2025677386 hasConcept C71924100 @default.
- W2025677386 hasConcept C76318530 @default.
- W2025677386 hasConceptScore W2025677386C126322002 @default.
- W2025677386 hasConceptScore W2025677386C141071460 @default.
- W2025677386 hasConceptScore W2025677386C142724271 @default.
- W2025677386 hasConceptScore W2025677386C2776376669 @default.
- W2025677386 hasConceptScore W2025677386C2778261982 @default.
- W2025677386 hasConceptScore W2025677386C2778382381 @default.
- W2025677386 hasConceptScore W2025677386C2779936836 @default.
- W2025677386 hasConceptScore W2025677386C2780434524 @default.
- W2025677386 hasConceptScore W2025677386C31174226 @default.
- W2025677386 hasConceptScore W2025677386C40993552 @default.
- W2025677386 hasConceptScore W2025677386C51915194 @default.
- W2025677386 hasConceptScore W2025677386C58471807 @default.
- W2025677386 hasConceptScore W2025677386C64841741 @default.
- W2025677386 hasConceptScore W2025677386C71924100 @default.
- W2025677386 hasConceptScore W2025677386C76318530 @default.
- W2025677386 hasIssue "10" @default.
- W2025677386 hasLocation W20256773861 @default.
- W2025677386 hasLocation W20256773862 @default.
- W2025677386 hasOpenAccess W2025677386 @default.
- W2025677386 hasPrimaryLocation W20256773861 @default.
- W2025677386 hasRelatedWork W1489103769 @default.
- W2025677386 hasRelatedWork W174106475 @default.
- W2025677386 hasRelatedWork W1976175088 @default.
- W2025677386 hasRelatedWork W2001757623 @default.
- W2025677386 hasRelatedWork W2099333384 @default.
- W2025677386 hasRelatedWork W2114096032 @default.
- W2025677386 hasRelatedWork W21266339 @default.
- W2025677386 hasRelatedWork W2145066374 @default.
- W2025677386 hasRelatedWork W2911666194 @default.
- W2025677386 hasRelatedWork W3110040994 @default.
- W2025677386 hasVolume "102" @default.
- W2025677386 isParatext "false" @default.
- W2025677386 isRetracted "false" @default.
- W2025677386 magId "2025677386" @default.
- W2025677386 workType "article" @default.