Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025679905> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2025679905 endingPage "585" @default.
- W2025679905 startingPage "575" @default.
- W2025679905 abstract "The effect of captopril, furosemide, indomethacin and intake of sodium on the production of PGI2-like material was studied in the rat aorta. Release of PGI2-like material from these vessels was estimated by its ability to inhibit ADP-induced platelet aggregation. Pretreatment with indomethacin (15 mg/kg/day) reduced the capacity of the aorta to release PGI2-like material. Pretreatment with captopril (10 mg/kg/day) had no effect. Intravenous furosemide (60 microgram/ml plasma volume) increased the capacity of the aorta to inhibit by 28% (p less than 0.25). The inhibitory capacity of aorta removed from rats on a low sodium diet did not differ from those on a high sodium diet. We conclude that the action of furosemide in reducing vascular tone may be related to stimulation of PGI2 synthesis in blood vessels whereas the effect of captopril and sodium in reducing vascular tone may involve a mechanism unrelated to PGI2 synthesis or may involve the synthesis of a prostaglandin other than PGI2." @default.
- W2025679905 created "2016-06-24" @default.
- W2025679905 creator A5061360691 @default.
- W2025679905 creator A5075013638 @default.
- W2025679905 date "1981-10-01" @default.
- W2025679905 modified "2023-09-23" @default.
- W2025679905 title "Release of prostaglandin I2-like activity from the rat aorta: Effect of captopril, furosemide, and sodium" @default.
- W2025679905 cites W1867365101 @default.
- W2025679905 cites W1911188572 @default.
- W2025679905 cites W1964341509 @default.
- W2025679905 cites W1967885105 @default.
- W2025679905 cites W1972609990 @default.
- W2025679905 cites W1986111942 @default.
- W2025679905 cites W2019014899 @default.
- W2025679905 cites W2022348680 @default.
- W2025679905 cites W2025061928 @default.
- W2025679905 cites W2030071404 @default.
- W2025679905 cites W2030768867 @default.
- W2025679905 cites W2046921348 @default.
- W2025679905 cites W2067165584 @default.
- W2025679905 cites W2070272847 @default.
- W2025679905 cites W2078343434 @default.
- W2025679905 cites W2085234634 @default.
- W2025679905 cites W2093452139 @default.
- W2025679905 cites W2313121787 @default.
- W2025679905 cites W2316505377 @default.
- W2025679905 cites W2400398107 @default.
- W2025679905 cites W2408403452 @default.
- W2025679905 cites W2413774153 @default.
- W2025679905 cites W2406462880 @default.
- W2025679905 doi "https://doi.org/10.1016/0090-6980(81)90067-8" @default.
- W2025679905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7034053" @default.
- W2025679905 hasPublicationYear "1981" @default.
- W2025679905 type Work @default.
- W2025679905 sameAs 2025679905 @default.
- W2025679905 citedByCount "23" @default.
- W2025679905 crossrefType "journal-article" @default.
- W2025679905 hasAuthorship W2025679905A5061360691 @default.
- W2025679905 hasAuthorship W2025679905A5075013638 @default.
- W2025679905 hasConcept C126322002 @default.
- W2025679905 hasConcept C134018914 @default.
- W2025679905 hasConcept C178790620 @default.
- W2025679905 hasConcept C185592680 @default.
- W2025679905 hasConcept C198710026 @default.
- W2025679905 hasConcept C24998067 @default.
- W2025679905 hasConcept C2777955127 @default.
- W2025679905 hasConcept C2779479957 @default.
- W2025679905 hasConcept C2779980429 @default.
- W2025679905 hasConcept C2780664492 @default.
- W2025679905 hasConcept C2909689315 @default.
- W2025679905 hasConcept C537181965 @default.
- W2025679905 hasConcept C55493867 @default.
- W2025679905 hasConcept C71924100 @default.
- W2025679905 hasConcept C84393581 @default.
- W2025679905 hasConcept C98274493 @default.
- W2025679905 hasConceptScore W2025679905C126322002 @default.
- W2025679905 hasConceptScore W2025679905C134018914 @default.
- W2025679905 hasConceptScore W2025679905C178790620 @default.
- W2025679905 hasConceptScore W2025679905C185592680 @default.
- W2025679905 hasConceptScore W2025679905C198710026 @default.
- W2025679905 hasConceptScore W2025679905C24998067 @default.
- W2025679905 hasConceptScore W2025679905C2777955127 @default.
- W2025679905 hasConceptScore W2025679905C2779479957 @default.
- W2025679905 hasConceptScore W2025679905C2779980429 @default.
- W2025679905 hasConceptScore W2025679905C2780664492 @default.
- W2025679905 hasConceptScore W2025679905C2909689315 @default.
- W2025679905 hasConceptScore W2025679905C537181965 @default.
- W2025679905 hasConceptScore W2025679905C55493867 @default.
- W2025679905 hasConceptScore W2025679905C71924100 @default.
- W2025679905 hasConceptScore W2025679905C84393581 @default.
- W2025679905 hasConceptScore W2025679905C98274493 @default.
- W2025679905 hasIssue "4" @default.
- W2025679905 hasLocation W20256799051 @default.
- W2025679905 hasLocation W20256799052 @default.
- W2025679905 hasOpenAccess W2025679905 @default.
- W2025679905 hasPrimaryLocation W20256799051 @default.
- W2025679905 hasRelatedWork W112590946 @default.
- W2025679905 hasRelatedWork W2006202112 @default.
- W2025679905 hasRelatedWork W2014570142 @default.
- W2025679905 hasRelatedWork W2022146609 @default.
- W2025679905 hasRelatedWork W2025679905 @default.
- W2025679905 hasRelatedWork W2042263844 @default.
- W2025679905 hasRelatedWork W2050711209 @default.
- W2025679905 hasRelatedWork W2054992011 @default.
- W2025679905 hasRelatedWork W2093518518 @default.
- W2025679905 hasRelatedWork W2168732577 @default.
- W2025679905 hasVolume "22" @default.
- W2025679905 isParatext "false" @default.
- W2025679905 isRetracted "false" @default.
- W2025679905 magId "2025679905" @default.
- W2025679905 workType "article" @default.