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- W2025713091 abstract "Here we report the first Staudinger ligations which yield tetra- and pentapeptides starting from N-terminal α-azido peptides and C-terminal peptide o-(diphenylphosphine)phenyl esters. Mass spectrometric analysis of the reaction mixture provided a better insight into the mechanism of the Staudinger ligation and has been used to explain the observed intermediates and to optimize the ligation reaction. As a result, the optimized reaction enables the chemoselective coupling of peptides containing amino acids other than glycine at the ligation site." @default.
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- W2025713091 date "2003-06-01" @default.
- W2025713091 modified "2023-10-15" @default.
- W2025713091 title "Chemoselective coupling of peptide fragments using the Staudinger ligation" @default.
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- W2025713091 doi "https://doi.org/10.1016/s0040-4039(03)01014-1" @default.
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