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• W2025753991 abstract "Paramylon, a β-(1→3)-D-glucan, isolated from Euglena gracilis, was tested for its adjuvant activity on the antibody response to sheep red blood cell (SRBC) in mice. Paramylon markedly enhanced anti-SRBC plaque-forming cell production at a dose of 10 mg/kg. It was also found that in vitro addition of lipopolysaccharide in culture to macrophages from paramylon-treated mice produced a large amount of interleukin 1 (IL-1) and there was a significant level of interleukin 6 (IL-6) induced transiently in the blood of these mice. As IL-1 and IL-6 play crucial roles in the immune response to T cell-dependent antigens like SRBC, the immunopotentiating effect of paramylon might be expressed through the action of these cytokines." @default.
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• W2025753991 date "1992-01-01" @default.
• W2025753991 modified "2023-10-03" @default.
• W2025753991 title "Cytokine-Related Immunopotentiating Activities of Paramylon, a .BETA.-(1.RAR.3)-D-Glucan from Euglena gracilis." @default.
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• W2025753991 doi "https://doi.org/10.1248/bpb1978.15.617" @default.
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