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- W2025756001 abstract "Abstract Objective The present cross-sectional study examined the relationships of psychopathology, side effects, and sociodemographic factors with treatment outcomes in terms of patients' quality of life (QOL), functioning, and needs for care. Method Sixty outpatients with chronic schizophrenia who had been treated with either clozapine or olanzapine for at least 6 months were investigated. Results Most psychopathological symptoms as well as psychic side effects, weight gain, and female sex were associated with lower QOL, while cognitive symptoms correlated with better QOL. Female sex, cognitive symptoms, and parkinsonism negatively influenced occupational functioning, and negative symptoms determined a lesser likelihood of living independently. Age, education, depression/anxiety, negative symptoms, and psychic side effects were predictors of patients' needs for care. Conclusion Our results highlight the complex nature of patient outcomes in schizophrenia. They reemphasize the need of targeting effectiveness, i.e. both symptomatic improvement as well as drug safety, in such patients." @default.
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- W2025756001 date "2005-08-01" @default.
- W2025756001 modified "2023-09-27" @default.
- W2025756001 title "Patient outcomes in schizophrenia I: correlates with sociodemographic variables, psychopathology, and side effects" @default.
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- W2025756001 doi "https://doi.org/10.1016/j.eurpsy.2005.02.005" @default.
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