FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025774756> ?p ?o ?g. }

• W2025774756 endingPage "834" @default.
• W2025774756 startingPage "828" @default.
• W2025774756 abstract "Objective Recombinant activated factor VII (rFVIIa) is being increasingly used in cardiac surgical patients with refractory hemorrhage. In this study, the authors assessed the ability of thromboelastography (TEG) in guiding rFVIIa therapy in this setting. Design Retrospective study. Setting Tertiary care university hospital. Participants Thirty-eight consecutive patients who received rFVIIa for refractory hemorrhage after cardiac surgery and had a complete coagulation profile including TEG within 30 minutes before and after rFVIIa. Interventions Standard coagulation (prothrombin time, partial thromboplastin time, platelet number, and fibrinogen) and TEG measurements (r time, k time, α angle, and maximum amplitude) before and after rFVIIa therapy were compared between responders and nonresponders (determined retrospectively based on clinical records). Measurements and Results Twenty-eight patients (74%) were classified as responders. There were no consistent changes in standard coagulation and TEG measurements before and after rFVIIa therapy. The number of abnormalities in pretreatment coagulation tests was related to response rates; odds of response were 11-fold (95% confidence interval [CI]) and 33-fold (95% CI) greater among patients with 0 or 1 abnormality in standard coagulation tests and TEG measures, respectively, than those with 2 or more abnormalities. Conclusions TEG may be a useful tool for predicting response to rFVIIa in the setting of refractory hemorrhage after cardiac surgery. Recombinant activated factor VII (rFVIIa) is being increasingly used in cardiac surgical patients with refractory hemorrhage. In this study, the authors assessed the ability of thromboelastography (TEG) in guiding rFVIIa therapy in this setting. Retrospective study. Tertiary care university hospital. Thirty-eight consecutive patients who received rFVIIa for refractory hemorrhage after cardiac surgery and had a complete coagulation profile including TEG within 30 minutes before and after rFVIIa. Standard coagulation (prothrombin time, partial thromboplastin time, platelet number, and fibrinogen) and TEG measurements (r time, k time, α angle, and maximum amplitude) before and after rFVIIa therapy were compared between responders and nonresponders (determined retrospectively based on clinical records). Twenty-eight patients (74%) were classified as responders. There were no consistent changes in standard coagulation and TEG measurements before and after rFVIIa therapy. The number of abnormalities in pretreatment coagulation tests was related to response rates; odds of response were 11-fold (95% confidence interval [CI]) and 33-fold (95% CI) greater among patients with 0 or 1 abnormality in standard coagulation tests and TEG measures, respectively, than those with 2 or more abnormalities. TEG may be a useful tool for predicting response to rFVIIa in the setting of refractory hemorrhage after cardiac surgery." @default.
• W2025774756 created "2016-06-24" @default.
• W2025774756 creator A5012269315 @default.
• W2025774756 creator A5027209386 @default.
• W2025774756 creator A5058767896 @default.
• W2025774756 creator A5075406446 @default.
• W2025774756 creator A5085988392 @default.
• W2025774756 date "2009-12-01" @default.
• W2025774756 modified "2023-10-16" @default.
• W2025774756 title "The Utility of Thromboelastography for Guiding Recombinant Activated Factor VII Therapy for Refractory Hemorrhage After Cardiac Surgery" @default.
• W2025774756 cites W1552116618 @default.
• W2025774756 cites W1561988912 @default.
• W2025774756 cites W1573466087 @default.
• W2025774756 cites W164154997 @default.
• W2025774756 cites W1965564230 @default.
• W2025774756 cites W1977148300 @default.
• W2025774756 cites W1983705991 @default.
• W2025774756 cites W1998105000 @default.
• W2025774756 cites W2028259055 @default.
• W2025774756 cites W2029733999 @default.
• W2025774756 cites W2038005163 @default.
• W2025774756 cites W2041614857 @default.
• W2025774756 cites W2049847471 @default.
• W2025774756 cites W2070158670 @default.
• W2025774756 cites W2080712219 @default.
• W2025774756 cites W2082353645 @default.
• W2025774756 cites W2094751056 @default.
• W2025774756 cites W2097406919 @default.
• W2025774756 cites W2121903458 @default.
• W2025774756 cites W2140699529 @default.
• W2025774756 cites W2143838598 @default.
• W2025774756 cites W2151327456 @default.
• W2025774756 cites W2164107296 @default.
• W2025774756 doi "https://doi.org/10.1053/j.jvca.2009.03.012" @default.
• W2025774756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19467888" @default.
• W2025774756 hasPublicationYear "2009" @default.
• W2025774756 type Work @default.
• W2025774756 sameAs 2025774756 @default.
• W2025774756 citedByCount "18" @default.
• W2025774756 countsByYear W20257747562012 @default.
• W2025774756 countsByYear W20257747562013 @default.
• W2025774756 countsByYear W20257747562014 @default.
• W2025774756 countsByYear W20257747562016 @default.
• W2025774756 countsByYear W20257747562017 @default.
• W2025774756 countsByYear W20257747562019 @default.
• W2025774756 countsByYear W20257747562023 @default.
• W2025774756 crossrefType "journal-article" @default.
• W2025774756 hasAuthorship W2025774756A5012269315 @default.
• W2025774756 hasAuthorship W2025774756A5027209386 @default.
• W2025774756 hasAuthorship W2025774756A5058767896 @default.
• W2025774756 hasAuthorship W2025774756A5075406446 @default.
• W2025774756 hasAuthorship W2025774756A5085988392 @default.
• W2025774756 hasConcept C121332964 @default.
• W2025774756 hasConcept C126322002 @default.
• W2025774756 hasConcept C141071460 @default.
• W2025774756 hasConcept C142424586 @default.
• W2025774756 hasConcept C16124881 @default.
• W2025774756 hasConcept C167135981 @default.
• W2025774756 hasConcept C26809991 @default.
• W2025774756 hasConcept C2777664302 @default.
• W2025774756 hasConcept C2778261982 @default.
• W2025774756 hasConcept C2778382381 @default.
• W2025774756 hasConcept C2778789114 @default.
• W2025774756 hasConcept C2778961111 @default.
• W2025774756 hasConcept C2779936836 @default.
• W2025774756 hasConcept C2780434524 @default.
• W2025774756 hasConcept C42219234 @default.
• W2025774756 hasConcept C71924100 @default.
• W2025774756 hasConcept C87355193 @default.
• W2025774756 hasConceptScore W2025774756C121332964 @default.
• W2025774756 hasConceptScore W2025774756C126322002 @default.
• W2025774756 hasConceptScore W2025774756C141071460 @default.
• W2025774756 hasConceptScore W2025774756C142424586 @default.
• W2025774756 hasConceptScore W2025774756C16124881 @default.
• W2025774756 hasConceptScore W2025774756C167135981 @default.
• W2025774756 hasConceptScore W2025774756C26809991 @default.
• W2025774756 hasConceptScore W2025774756C2777664302 @default.
• W2025774756 hasConceptScore W2025774756C2778261982 @default.
• W2025774756 hasConceptScore W2025774756C2778382381 @default.
• W2025774756 hasConceptScore W2025774756C2778789114 @default.
• W2025774756 hasConceptScore W2025774756C2778961111 @default.
• W2025774756 hasConceptScore W2025774756C2779936836 @default.
• W2025774756 hasConceptScore W2025774756C2780434524 @default.
• W2025774756 hasConceptScore W2025774756C42219234 @default.
• W2025774756 hasConceptScore W2025774756C71924100 @default.
• W2025774756 hasConceptScore W2025774756C87355193 @default.
• W2025774756 hasIssue "6" @default.
• W2025774756 hasLocation W20257747561 @default.
• W2025774756 hasLocation W20257747562 @default.
• W2025774756 hasOpenAccess W2025774756 @default.
• W2025774756 hasPrimaryLocation W20257747561 @default.
• W2025774756 hasRelatedWork W1907544254 @default.
• W2025774756 hasRelatedWork W2588493708 @default.
• W2025774756 hasRelatedWork W2660767330 @default.
• W2025774756 hasRelatedWork W2793874131 @default.
• W2025774756 hasRelatedWork W2951281702 @default.
• W2025774756 hasRelatedWork W3003294560 @default.
• W2025774756 hasRelatedWork W3013706480 @default.

• next