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• W2025781389 abstract "Mitogen-activated protein (MAP) kinases are activated in response to a variety of extracellular stimuli by phosphorylation on tyrosine and threonine residues. Xp42 is a Xenopus laevis MAP kinase that is activated during oocyte maturation. Modified forms of Xp42 that lacked enzymatic activity or either of the phosphorylation sites were expressed in Xenopus oocytes. When meiotic maturation was induced with progesterone, each mutant Xp42 was phosphorylated, indicating that at least one kinase was activated that can phosphorylate Xp42 on tyrosine and threonine. Phosphorylation of one residue is not strictly dependent on phosphorylation of the other." @default.
• W2025781389 created "2016-06-24" @default.
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• W2025781389 date "1992-01-10" @default.
• W2025781389 modified "2023-10-16" @default.
• W2025781389 title "Requirements for Phosphorylation of Map Kinase During Meiosis in <i>Xenopus</i> Oocytes" @default.
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• W2025781389 doi "https://doi.org/10.1126/science.1313186" @default.
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