FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025835612> ?p ?o ?g. }

• W2025835612 endingPage "323" @default.
• W2025835612 startingPage "308" @default.
• W2025835612 abstract "1. The production of cyclic adenosine 3':5'-monophosphate (cyclic AMP) and corticosterone isolated ratadrenal cells was increased by cholera enterotoxin. Both responses were accompanied by a lag period which is characteristic of other known actions of enterotoxin. The duration of the lag period in the production of corticosterone depended on the concentration of enterotoxin; with the maximally stimulating amounts it was 30-45 min. 2. Maximum rates of cyclic AMP and corticosterone synthesis, after the lag period, were constant for at least 1 h. Although the maximum rate of corticosterone formation was the same as that obtained adrenocorticotropic hormone, the maximum rate of cyclic AMP formation was only 8-10% of that with adrenocorticotropic hormone. 3. Pretreatment of the cells with enterotoxin ahd no effect on their subsequent steroidogenic response to maximally stimulating amounts of adrenocorticotropic hormone. 4. Cycloheximide inhibited the effect of both enterotoxin and adrenocorticotropic hormone on corticosterone production. 5. Enterotoxin stimulation of both cyclic AMP and corticosterone formation was dependent on the presence of Ca2+ in the medium although the Ca2+ requirement was not same as that for adrenocorticotropic hormone. Thus, EGTA at concentrations which completely abolished the effect of adrenocorticotropic hormone caused only a partial reduction in the effects of enterotoxin. 6. Exogenously added choleragenoid and gangliosides abolished the effects of enterotoxin without having any significant effect on the response of the cells to adrenocorticotropic hormone. 7. After treatment with neuraminidase, the adrenal cells showed an increased response to enterotoxin in terms of both cyclic AMP and corticosterone formation which was due to a combination of two effects: (a) increased rate of synthesis of both compounds and (b) shortening of the characteristic lag period. This is in sharp contrast to the results obtained with adrenocorticotropic hormone where neuraminidase-treatment made the cells less sensitive to adrenocorticotropic hormone." @default.
• W2025835612 created "2016-06-24" @default.
• W2025835612 creator A5013064838 @default.
• W2025835612 creator A5032242216 @default.
• W2025835612 creator A5033827654 @default.
• W2025835612 date "1975-02-01" @default.
• W2025835612 modified "2023-09-23" @default.
• W2025835612 title "Stimulation of cyclic adenosine 3′:5′-monophosphate and corticosterone formation in isolated rat adrenal cells by cholera ente rotoxin comparison with the effects of ACTH" @default.
• W2025835612 cites W1511454777 @default.
• W2025835612 cites W1956627733 @default.
• W2025835612 cites W1960281573 @default.
• W2025835612 cites W1975906128 @default.
• W2025835612 cites W1981089905 @default.
• W2025835612 cites W1988371502 @default.
• W2025835612 cites W1991204762 @default.
• W2025835612 cites W1994016956 @default.
• W2025835612 cites W1996497544 @default.
• W2025835612 cites W2000080153 @default.
• W2025835612 cites W2016390730 @default.
• W2025835612 cites W2017058877 @default.
• W2025835612 cites W2017968122 @default.
• W2025835612 cites W2018392851 @default.
• W2025835612 cites W2023601764 @default.
• W2025835612 cites W2026264692 @default.
• W2025835612 cites W2028133745 @default.
• W2025835612 cites W2033286224 @default.
• W2025835612 cites W2040496537 @default.
• W2025835612 cites W2043475832 @default.
• W2025835612 cites W2043657835 @default.
• W2025835612 cites W2045857150 @default.
• W2025835612 cites W2046072956 @default.
• W2025835612 cites W2046628065 @default.
• W2025835612 cites W2057890140 @default.
• W2025835612 cites W2061029816 @default.
• W2025835612 cites W2066765300 @default.
• W2025835612 cites W2067109129 @default.
• W2025835612 cites W2067310997 @default.
• W2025835612 cites W2087278833 @default.
• W2025835612 cites W2089264852 @default.
• W2025835612 cites W2091705584 @default.
• W2025835612 cites W2112244510 @default.
• W2025835612 cites W2138243399 @default.
• W2025835612 cites W2165932004 @default.
• W2025835612 cites W2167931286 @default.
• W2025835612 cites W2189491718 @default.
• W2025835612 cites W2316169353 @default.
• W2025835612 cites W2328287470 @default.
• W2025835612 cites W2334683910 @default.
• W2025835612 cites W4237141439 @default.
• W2025835612 cites W4245175588 @default.
• W2025835612 cites W45574617 @default.
• W2025835612 cites W85152717 @default.
• W2025835612 doi "https://doi.org/10.1016/0304-4165(75)90237-8" @default.
• W2025835612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/163102" @default.
• W2025835612 hasPublicationYear "1975" @default.
• W2025835612 type Work @default.
• W2025835612 sameAs 2025835612 @default.
• W2025835612 citedByCount "25" @default.
• W2025835612 crossrefType "journal-article" @default.
• W2025835612 hasAuthorship W2025835612A5013064838 @default.
• W2025835612 hasAuthorship W2025835612A5032242216 @default.
• W2025835612 hasAuthorship W2025835612A5033827654 @default.
• W2025835612 hasConcept C126322002 @default.
• W2025835612 hasConcept C134018914 @default.
• W2025835612 hasConcept C170493617 @default.
• W2025835612 hasConcept C177865409 @default.
• W2025835612 hasConcept C185592680 @default.
• W2025835612 hasConcept C24998067 @default.
• W2025835612 hasConcept C2776668983 @default.
• W2025835612 hasConcept C2777006276 @default.
• W2025835612 hasConcept C2780352252 @default.
• W2025835612 hasConcept C2780546910 @default.
• W2025835612 hasConcept C71315377 @default.
• W2025835612 hasConcept C71924100 @default.
• W2025835612 hasConcept C86803240 @default.
• W2025835612 hasConceptScore W2025835612C126322002 @default.
• W2025835612 hasConceptScore W2025835612C134018914 @default.
• W2025835612 hasConceptScore W2025835612C170493617 @default.
• W2025835612 hasConceptScore W2025835612C177865409 @default.
• W2025835612 hasConceptScore W2025835612C185592680 @default.
• W2025835612 hasConceptScore W2025835612C24998067 @default.
• W2025835612 hasConceptScore W2025835612C2776668983 @default.
• W2025835612 hasConceptScore W2025835612C2777006276 @default.
• W2025835612 hasConceptScore W2025835612C2780352252 @default.
• W2025835612 hasConceptScore W2025835612C2780546910 @default.
• W2025835612 hasConceptScore W2025835612C71315377 @default.
• W2025835612 hasConceptScore W2025835612C71924100 @default.
• W2025835612 hasConceptScore W2025835612C86803240 @default.
• W2025835612 hasIssue "2" @default.
• W2025835612 hasLocation W20258356121 @default.
• W2025835612 hasLocation W20258356122 @default.
• W2025835612 hasOpenAccess W2025835612 @default.
• W2025835612 hasPrimaryLocation W20258356121 @default.
• W2025835612 hasRelatedWork W100928883 @default.
• W2025835612 hasRelatedWork W2009952201 @default.
• W2025835612 hasRelatedWork W2021595401 @default.
• W2025835612 hasRelatedWork W2025835612 @default.
• W2025835612 hasRelatedWork W2061601189 @default.

• next