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- W202587114 abstract "The technique of sentinel lymph node biopsy has permitted accurate identification by surgeons and nuclear medicine physicians of the first node to receive direct drainage from an area of tumor. This selective dissection of the first draining node has had the added benefit of dramatically reducing the number of nodes the pathologist must examine in the search for metastatic tumor. This in turn has made feasible the routine examination of multiple levels of the submitted lymph node tissue and the routine use of immunohistochemical stains, both of which had been proven, even in the pre-sentinel lymph node era, to improve detection of occult metastases, which impart a poor prognosis. While the optimal method for pathologic examination of the sentinel lymph node remains “a work in progress”, examination of at least three levels of the block, and the routine use of immunohistochemical stains for antigens such as S-100 (for melanoma) and keratin proteins (for carcinoma) seems to constitute the current “standard of care”. The value of highly sensitive methods, such as PCR, in the search for occult metastases remains a subject of active investigation." @default.
- W202587114 created "2016-06-24" @default.
- W202587114 creator A5040242774 @default.
- W202587114 date "2005-12-28" @default.
- W202587114 modified "2023-09-23" @default.
- W202587114 title "Pathologic Examination of the Sentinel Lymph Node" @default.
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- W202587114 doi "https://doi.org/10.1007/0-306-47822-6_5" @default.
- W202587114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12380176" @default.
- W202587114 hasPublicationYear "2005" @default.
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