FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025880416> ?p ?o ?g. }

• W2025880416 endingPage "1374" @default.
• W2025880416 startingPage "1368" @default.
• W2025880416 abstract "Background Acute studies have suggested that left ventricular pacing (LVP) may have benefits over biventricular pacing (BVP). The adaptive cardiac resynchronization therapy (aCRT) algorithm provides LVP synchronized to produce fusion with the intrinsic activation when the intrinsic atrioventricular (AV) interval is normal. The randomized double-blind adaptive cardiac resynchronization therapy trial demonstrated noninferiority of the aCRT algorithm compared to echocardiography-optimized BVP (control). Objective To examine whether synchronized LVP (sLVP) resulted in better clinical outcomes. Methods First, stratification by percent sLVP (%sLVP) and multivariate Cox proportional hazards model was used to assess the relationship between %sLVP and clinical outcomes. Second, outcomes were compared between patients in the aCRT arm (n = 318) and control patients (n = 160) stratified by intrinsic AV interval at randomization. Results In the aCRT arm, %sLVP ≥50% (n = 142) was independently associated with a decreased risk of death or heart failure hospitalization (hazard ratio 0.49; 95% confidence interval 0.28–0.85; P = .012) compared with %sLVP <50% (n = 172). A greater proportion of patients with %sLVP ≥50% improved in Packer’s clinical composite score at 6-month (82% vs 68%; P = .002) and 12-month (80% vs 62%; P = .0006) follow-ups compared to controls. In the subgroup with normal AV (n = 241), there was a lower risk of death or heart failure hospitalization (hazard ratio 0.52; 95% confidence interval 0.27–0.98; P = .044) with the aCRT algorithm. A greater proportion of patients in the aCRT arm improved in the clinical composite score at 6-month (81% vs 69%; P = .041) and 12-month (77% vs 66%; P = .076) follow-ups compared to controls. Conclusions Higher %sLVP was independently associated with superior clinical outcomes. In patients with normal AV conduction, the aCRT algorithm provided mostly sLVP and demonstrated better clinical outcomes compared to echocardiography-optimized BVP. Acute studies have suggested that left ventricular pacing (LVP) may have benefits over biventricular pacing (BVP). The adaptive cardiac resynchronization therapy (aCRT) algorithm provides LVP synchronized to produce fusion with the intrinsic activation when the intrinsic atrioventricular (AV) interval is normal. The randomized double-blind adaptive cardiac resynchronization therapy trial demonstrated noninferiority of the aCRT algorithm compared to echocardiography-optimized BVP (control). To examine whether synchronized LVP (sLVP) resulted in better clinical outcomes. First, stratification by percent sLVP (%sLVP) and multivariate Cox proportional hazards model was used to assess the relationship between %sLVP and clinical outcomes. Second, outcomes were compared between patients in the aCRT arm (n = 318) and control patients (n = 160) stratified by intrinsic AV interval at randomization. In the aCRT arm, %sLVP ≥50% (n = 142) was independently associated with a decreased risk of death or heart failure hospitalization (hazard ratio 0.49; 95% confidence interval 0.28–0.85; P = .012) compared with %sLVP <50% (n = 172). A greater proportion of patients with %sLVP ≥50% improved in Packer’s clinical composite score at 6-month (82% vs 68%; P = .002) and 12-month (80% vs 62%; P = .0006) follow-ups compared to controls. In the subgroup with normal AV (n = 241), there was a lower risk of death or heart failure hospitalization (hazard ratio 0.52; 95% confidence interval 0.27–0.98; P = .044) with the aCRT algorithm. A greater proportion of patients in the aCRT arm improved in the clinical composite score at 6-month (81% vs 69%; P = .041) and 12-month (77% vs 66%; P = .076) follow-ups compared to controls. Higher %sLVP was independently associated with superior clinical outcomes. In patients with normal AV conduction, the aCRT algorithm provided mostly sLVP and demonstrated better clinical outcomes compared to echocardiography-optimized BVP." @default.
• W2025880416 created "2016-06-24" @default.
• W2025880416 creator A5020327977 @default.
• W2025880416 creator A5021169264 @default.
• W2025880416 creator A5021834665 @default.
• W2025880416 creator A5022557025 @default.
• W2025880416 creator A5022913157 @default.
• W2025880416 creator A5039589228 @default.
• W2025880416 creator A5055155626 @default.
• W2025880416 creator A5059572789 @default.
• W2025880416 creator A5059708139 @default.
• W2025880416 creator A5071772915 @default.
• W2025880416 creator A5072241191 @default.
• W2025880416 creator A5078388970 @default.
• W2025880416 creator A5079387266 @default.
• W2025880416 date "2013-09-01" @default.
• W2025880416 modified "2023-10-01" @default.
• W2025880416 title "Clinical outcomes with synchronized left ventricular pacing: Analysis of the adaptive CRT trial" @default.
• W2025880416 cites W1976177045 @default.
• W2025880416 cites W1977301303 @default.
• W2025880416 cites W2011222078 @default.
• W2025880416 cites W2015697923 @default.
• W2025880416 cites W2017265142 @default.
• W2025880416 cites W2020811427 @default.
• W2025880416 cites W2044796943 @default.
• W2025880416 cites W2048056747 @default.
• W2025880416 cites W2053172478 @default.
• W2025880416 cites W2060319585 @default.
• W2025880416 cites W2072296701 @default.
• W2025880416 cites W2074760813 @default.
• W2025880416 cites W2077051047 @default.
• W2025880416 cites W2084147795 @default.
• W2025880416 cites W2087632582 @default.
• W2025880416 cites W2094025083 @default.
• W2025880416 cites W2130907431 @default.
• W2025880416 cites W2140552312 @default.
• W2025880416 cites W2142210779 @default.
• W2025880416 cites W2159978316 @default.
• W2025880416 cites W2395162120 @default.
• W2025880416 cites W3144470180 @default.
• W2025880416 cites W4361868645 @default.
• W2025880416 doi "https://doi.org/10.1016/j.hrthm.2013.07.007" @default.
• W2025880416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23851059" @default.
• W2025880416 hasPublicationYear "2013" @default.
• W2025880416 type Work @default.
• W2025880416 sameAs 2025880416 @default.
• W2025880416 citedByCount "137" @default.
• W2025880416 countsByYear W20258804162013 @default.
• W2025880416 countsByYear W20258804162014 @default.
• W2025880416 countsByYear W20258804162015 @default.
• W2025880416 countsByYear W20258804162016 @default.
• W2025880416 countsByYear W20258804162017 @default.
• W2025880416 countsByYear W20258804162018 @default.
• W2025880416 countsByYear W20258804162019 @default.
• W2025880416 countsByYear W20258804162020 @default.
• W2025880416 countsByYear W20258804162021 @default.
• W2025880416 countsByYear W20258804162022 @default.
• W2025880416 countsByYear W20258804162023 @default.
• W2025880416 crossrefType "journal-article" @default.
• W2025880416 hasAuthorship W2025880416A5020327977 @default.
• W2025880416 hasAuthorship W2025880416A5021169264 @default.
• W2025880416 hasAuthorship W2025880416A5021834665 @default.
• W2025880416 hasAuthorship W2025880416A5022557025 @default.
• W2025880416 hasAuthorship W2025880416A5022913157 @default.
• W2025880416 hasAuthorship W2025880416A5039589228 @default.
• W2025880416 hasAuthorship W2025880416A5055155626 @default.
• W2025880416 hasAuthorship W2025880416A5059572789 @default.
• W2025880416 hasAuthorship W2025880416A5059708139 @default.
• W2025880416 hasAuthorship W2025880416A5071772915 @default.
• W2025880416 hasAuthorship W2025880416A5072241191 @default.
• W2025880416 hasAuthorship W2025880416A5078388970 @default.
• W2025880416 hasAuthorship W2025880416A5079387266 @default.
• W2025880416 hasConcept C11413529 @default.
• W2025880416 hasConcept C126322002 @default.
• W2025880416 hasConcept C164705383 @default.
• W2025880416 hasConcept C168563851 @default.
• W2025880416 hasConcept C204243189 @default.
• W2025880416 hasConcept C207103383 @default.
• W2025880416 hasConcept C2776034619 @default.
• W2025880416 hasConcept C2778198053 @default.
• W2025880416 hasConcept C41008148 @default.
• W2025880416 hasConcept C44249647 @default.
• W2025880416 hasConcept C50382708 @default.
• W2025880416 hasConcept C535046627 @default.
• W2025880416 hasConcept C71924100 @default.
• W2025880416 hasConcept C78085059 @default.
• W2025880416 hasConceptScore W2025880416C11413529 @default.
• W2025880416 hasConceptScore W2025880416C126322002 @default.
• W2025880416 hasConceptScore W2025880416C164705383 @default.
• W2025880416 hasConceptScore W2025880416C168563851 @default.
• W2025880416 hasConceptScore W2025880416C204243189 @default.
• W2025880416 hasConceptScore W2025880416C207103383 @default.
• W2025880416 hasConceptScore W2025880416C2776034619 @default.
• W2025880416 hasConceptScore W2025880416C2778198053 @default.
• W2025880416 hasConceptScore W2025880416C41008148 @default.
• W2025880416 hasConceptScore W2025880416C44249647 @default.
• W2025880416 hasConceptScore W2025880416C50382708 @default.
• W2025880416 hasConceptScore W2025880416C535046627 @default.

• next