FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025882685> ?p ?o ?g. }

• W2025882685 endingPage "1633" @default.
• W2025882685 startingPage "1623" @default.
• W2025882685 abstract "To investigate the impact of rosiglitazone therapy on lipid profiles, glycemic control, and costs associated with cholesterol-lowering and diabetic medications among Type 2 diabetes mellitus (T2DM) patients in a standard practice setting.This retrospective cohort study was conducted using data from the General Practice Research Database during 1999-2006. T2DM patients were classified based on the addition of rosiglitazone versus either metformin or a sulfonylurea ('comparison group') to pre-existing glucose lowering agents. After propensity score matching to control for differences in baseline patient characteristics, 1450 matched pairs were identified. The mean changes in total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), glycosylated hemoglobin A1C (A1C), and daily medication costs were calculated. To investigate the incremental costs for lipid-lowering medications, a two-part model was utilized.The mean changes in TC and A1C for the rosiglitazone and metformin/sulfonylurea groups were 9 vs -10 mg/dL for TC, -2 vs -9 mg/dL for LDL-C, and -0.8% vs. -1.2% for A1C, respectively. The mean changes in daily medication costs of glucose- and lipid-lowering drugs were $3.95 for rosiglitazone patients and $0.27 for metformin/sulfonylurea patients. For patients with positive incremental lipid-lowering costs, rosiglitazone use was significantly associated with costs eight times greater than metformin/sulfonylureas. Generalizability of the study is limited due to cost estimates using the national formulary and potential selection bias.Addition of rosiglitazone to an existing antidiabetic medication regimen improved glycemic control to a lesser extent than metformin/sulfonylurea, and also deteriorated patients' lipid profiles, leading to significantly greater daily costs. Economic evaluations of alternative therapies should consider such costs to estimate the full impact of different therapeutic approaches in diabetes." @default.
• W2025882685 created "2016-06-24" @default.
• W2025882685 creator A5007920767 @default.
• W2025882685 creator A5026253548 @default.
• W2025882685 creator A5037053970 @default.
• W2025882685 creator A5069119629 @default.
• W2025882685 date "2011-06-22" @default.
• W2025882685 modified "2023-09-23" @default.
• W2025882685 title "Impact of rosiglitazone therapy on the lipid profile, glycemic control, and medication costs among type 2 diabetes patients" @default.
• W2025882685 cites W1691887444 @default.
• W2025882685 cites W1963886325 @default.
• W2025882685 cites W1975777549 @default.
• W2025882685 cites W1976567448 @default.
• W2025882685 cites W1977386411 @default.
• W2025882685 cites W1981075911 @default.
• W2025882685 cites W1982990554 @default.
• W2025882685 cites W1986229866 @default.
• W2025882685 cites W1989377468 @default.
• W2025882685 cites W1997030483 @default.
• W2025882685 cites W1998418707 @default.
• W2025882685 cites W2001031717 @default.
• W2025882685 cites W2019304391 @default.
• W2025882685 cites W2020267609 @default.
• W2025882685 cites W2033945449 @default.
• W2025882685 cites W2034177557 @default.
• W2025882685 cites W2040492681 @default.
• W2025882685 cites W2056726092 @default.
• W2025882685 cites W2074047111 @default.
• W2025882685 cites W2076781345 @default.
• W2025882685 cites W2083780750 @default.
• W2025882685 cites W2086377769 @default.
• W2025882685 cites W2090255610 @default.
• W2025882685 cites W2096430659 @default.
• W2025882685 cites W2102675827 @default.
• W2025882685 cites W2106406559 @default.
• W2025882685 cites W2107298817 @default.
• W2025882685 cites W2120822075 @default.
• W2025882685 cites W2122130517 @default.
• W2025882685 cites W2127125241 @default.
• W2025882685 cites W2129563195 @default.
• W2025882685 cites W2131669718 @default.
• W2025882685 cites W2136628182 @default.
• W2025882685 cites W2167359851 @default.
• W2025882685 cites W2169421904 @default.
• W2025882685 cites W2329556022 @default.
• W2025882685 cites W2410894703 @default.
• W2025882685 cites W2416965252 @default.
• W2025882685 cites W3124564277 @default.
• W2025882685 doi "https://doi.org/10.1185/03007995.2011.595001" @default.
• W2025882685 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21696266" @default.
• W2025882685 hasPublicationYear "2011" @default.
• W2025882685 type Work @default.
• W2025882685 sameAs 2025882685 @default.
• W2025882685 citedByCount "4" @default.
• W2025882685 countsByYear W20258826852012 @default.
• W2025882685 countsByYear W20258826852013 @default.
• W2025882685 countsByYear W20258826852015 @default.
• W2025882685 countsByYear W20258826852017 @default.
• W2025882685 crossrefType "journal-article" @default.
• W2025882685 hasAuthorship W2025882685A5007920767 @default.
• W2025882685 hasAuthorship W2025882685A5026253548 @default.
• W2025882685 hasAuthorship W2025882685A5037053970 @default.
• W2025882685 hasAuthorship W2025882685A5069119629 @default.
• W2025882685 hasConcept C126322002 @default.
• W2025882685 hasConcept C134018914 @default.
• W2025882685 hasConcept C2777180221 @default.
• W2025882685 hasConcept C2778163477 @default.
• W2025882685 hasConcept C2778270857 @default.
• W2025882685 hasConcept C2778854520 @default.
• W2025882685 hasConcept C2779306644 @default.
• W2025882685 hasConcept C2780152017 @default.
• W2025882685 hasConcept C2780323712 @default.
• W2025882685 hasConcept C2780473172 @default.
• W2025882685 hasConcept C555293320 @default.
• W2025882685 hasConcept C71924100 @default.
• W2025882685 hasConceptScore W2025882685C126322002 @default.
• W2025882685 hasConceptScore W2025882685C134018914 @default.
• W2025882685 hasConceptScore W2025882685C2777180221 @default.
• W2025882685 hasConceptScore W2025882685C2778163477 @default.
• W2025882685 hasConceptScore W2025882685C2778270857 @default.
• W2025882685 hasConceptScore W2025882685C2778854520 @default.
• W2025882685 hasConceptScore W2025882685C2779306644 @default.
• W2025882685 hasConceptScore W2025882685C2780152017 @default.
• W2025882685 hasConceptScore W2025882685C2780323712 @default.
• W2025882685 hasConceptScore W2025882685C2780473172 @default.
• W2025882685 hasConceptScore W2025882685C555293320 @default.
• W2025882685 hasConceptScore W2025882685C71924100 @default.
• W2025882685 hasIssue "8" @default.
• W2025882685 hasLocation W20258826851 @default.
• W2025882685 hasLocation W20258826852 @default.
• W2025882685 hasOpenAccess W2025882685 @default.
• W2025882685 hasPrimaryLocation W20258826851 @default.
• W2025882685 hasRelatedWork W1996010611 @default.
• W2025882685 hasRelatedWork W2072752555 @default.
• W2025882685 hasRelatedWork W2087748897 @default.
• W2025882685 hasRelatedWork W2107068945 @default.
• W2025882685 hasRelatedWork W2274802177 @default.
• W2025882685 hasRelatedWork W2285422143 @default.

• next