FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025886796> ?p ?o ?g. }

• W2025886796 endingPage "419" @default.
• W2025886796 startingPage "411" @default.
• W2025886796 abstract "Aims To retrospectively review the toxicity and early outcome data from patients who have received stereotactic body radiotherapy (SBRT) for extracranial oligometastases at a single UK institution. Materials and methods Eligible patients had ≤3 extracranial metastases and performance status ≤2. Prior systemic therapy and radical treatment of oligometastastic relapse with any standard treatment modality was permitted. Patients with synchronous metastatic disease were excluded unless they had evidence of controlled primary disease after radical therapy. Follow-up consisted of clinical examination, biochemical and radiological assessments in accordance with standard clinical care. Progression events were defined using RECIST. Toxicity was evaluated using CTCAE v4.0. Local control, progression-free survival (PFS), freedom from widespread distant metastasis (defined as disease not amenable to further radical salvage therapy) and overall survival were calculated. Results Between July 2011 and April 2014, 73 patients with 87 metastases received SBRT (range 1–3 per patient). The median follow-up was 14.5 months (range 0–26.4). The median PFS was 14.5 months (1 year PFS 57%, 2 year 28%); 1 year overall survival 96%, 2 year 79.8%; 2 year local control 88%. At 2 years, 46% of patients were free from widespread distant metastases. No ≥ grade 3 acute or late toxicity was observed. Conclusion At this time point, observed toxicity is minimal with excellent local control rates. This promising treatment paradigm requires further investigation in the context of a randomised controlled trial to establish if the addition of SBRT to standard care improves survival outcomes." @default.
• W2025886796 created "2016-06-24" @default.
• W2025886796 creator A5009984723 @default.
• W2025886796 creator A5015984938 @default.
• W2025886796 creator A5016241442 @default.
• W2025886796 creator A5030248496 @default.
• W2025886796 creator A5033672260 @default.
• W2025886796 creator A5041059810 @default.
• W2025886796 creator A5047171631 @default.
• W2025886796 creator A5051619581 @default.
• W2025886796 creator A5058395730 @default.
• W2025886796 creator A5062343021 @default.
• W2025886796 creator A5068847821 @default.
• W2025886796 creator A5080362183 @default.
• W2025886796 creator A5081207445 @default.
• W2025886796 creator A5086729787 @default.
• W2025886796 date "2015-07-01" @default.
• W2025886796 modified "2023-09-25" @default.
• W2025886796 title "Initial UK Experience of Stereotactic Body Radiotherapy for Extracranial Oligometastases: Can We Change the Therapeutic Paradigm?" @default.
• W2025886796 cites W1528207664 @default.
• W2025886796 cites W1963798982 @default.
• W2025886796 cites W1969531640 @default.
• W2025886796 cites W1982200074 @default.
• W2025886796 cites W1992007584 @default.
• W2025886796 cites W2003218091 @default.
• W2025886796 cites W2019607817 @default.
• W2025886796 cites W2024501410 @default.
• W2025886796 cites W2026656096 @default.
• W2025886796 cites W2030505692 @default.
• W2025886796 cites W2031688279 @default.
• W2025886796 cites W2035133028 @default.
• W2025886796 cites W2042740351 @default.
• W2025886796 cites W2043853087 @default.
• W2025886796 cites W2054974480 @default.
• W2025886796 cites W2070681106 @default.
• W2025886796 cites W2090749716 @default.
• W2025886796 cites W2094000412 @default.
• W2025886796 cites W2108463536 @default.
• W2025886796 cites W2111247556 @default.
• W2025886796 cites W2117832658 @default.
• W2025886796 cites W2127240958 @default.
• W2025886796 cites W2131110909 @default.
• W2025886796 cites W2136706275 @default.
• W2025886796 cites W2140110477 @default.
• W2025886796 cites W2142138307 @default.
• W2025886796 cites W2143047117 @default.
• W2025886796 cites W2144574555 @default.
• W2025886796 cites W2159746573 @default.
• W2025886796 cites W2160166879 @default.
• W2025886796 cites W2212472250 @default.
• W2025886796 cites W326741768 @default.
• W2025886796 cites W4230791750 @default.
• W2025886796 cites W4240340450 @default.
• W2025886796 doi "https://doi.org/10.1016/j.clon.2015.03.006" @default.
• W2025886796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25912366" @default.
• W2025886796 hasPublicationYear "2015" @default.
• W2025886796 type Work @default.
• W2025886796 sameAs 2025886796 @default.
• W2025886796 citedByCount "27" @default.
• W2025886796 countsByYear W20258867962015 @default.
• W2025886796 countsByYear W20258867962016 @default.
• W2025886796 countsByYear W20258867962017 @default.
• W2025886796 countsByYear W20258867962018 @default.
• W2025886796 countsByYear W20258867962019 @default.
• W2025886796 countsByYear W20258867962020 @default.
• W2025886796 countsByYear W20258867962021 @default.
• W2025886796 countsByYear W20258867962022 @default.
• W2025886796 crossrefType "journal-article" @default.
• W2025886796 hasAuthorship W2025886796A5009984723 @default.
• W2025886796 hasAuthorship W2025886796A5015984938 @default.
• W2025886796 hasAuthorship W2025886796A5016241442 @default.
• W2025886796 hasAuthorship W2025886796A5030248496 @default.
• W2025886796 hasAuthorship W2025886796A5033672260 @default.
• W2025886796 hasAuthorship W2025886796A5041059810 @default.
• W2025886796 hasAuthorship W2025886796A5047171631 @default.
• W2025886796 hasAuthorship W2025886796A5051619581 @default.
• W2025886796 hasAuthorship W2025886796A5058395730 @default.
• W2025886796 hasAuthorship W2025886796A5062343021 @default.
• W2025886796 hasAuthorship W2025886796A5068847821 @default.
• W2025886796 hasAuthorship W2025886796A5080362183 @default.
• W2025886796 hasAuthorship W2025886796A5081207445 @default.
• W2025886796 hasAuthorship W2025886796A5086729787 @default.
• W2025886796 hasConcept C126322002 @default.
• W2025886796 hasConcept C141071460 @default.
• W2025886796 hasConcept C151730666 @default.
• W2025886796 hasConcept C168563851 @default.
• W2025886796 hasConcept C190892606 @default.
• W2025886796 hasConcept C203092338 @default.
• W2025886796 hasConcept C2776694085 @default.
• W2025886796 hasConcept C2778822529 @default.
• W2025886796 hasConcept C2779343474 @default.
• W2025886796 hasConcept C2779984678 @default.
• W2025886796 hasConcept C2780387249 @default.
• W2025886796 hasConcept C2780739268 @default.
• W2025886796 hasConcept C2780775027 @default.
• W2025886796 hasConcept C29730261 @default.
• W2025886796 hasConcept C509974204 @default.
• W2025886796 hasConcept C535046627 @default.

• next