Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025894961> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2025894961 abstract "A critical open problem in emph{ab initio} protein folding is protein energy function design, which pertains to defining the energy of protein conformations in a way that makes folding most efficient and reliable. In this paper, we address this issue as a weight optimization problem and utilize a machine learning approach, learning-to-rank, to solve this problem. We investigate the ranking-via-classification approach, especially the Ranking SVM method and compare it with the state-of-the-art approach to the problem using the MINUIT optimization package. To maintain the physicality of the results, we impose non-negativity constraints on the weights. For this we develop two efficient non-negative support vector machine (NNSVM) methods, derived from L2-norm SVM and L1-norm SVMs, respectively. We demonstrate an energy function which maintains the correct ordering with respect to structure dissimilarity to the native state more often, is more efficient and reliable for learning on large protein sets, and is qualitatively superior to the current state-of-the-art energy function." @default.
- W2025894961 created "2016-06-24" @default.
- W2025894961 creator A5005255629 @default.
- W2025894961 creator A5010808261 @default.
- W2025894961 creator A5011303933 @default.
- W2025894961 creator A5037119402 @default.
- W2025894961 creator A5040719512 @default.
- W2025894961 creator A5071397525 @default.
- W2025894961 creator A5074570646 @default.
- W2025894961 creator A5084686197 @default.
- W2025894961 date "2011-12-01" @default.
- W2025894961 modified "2023-10-02" @default.
- W2025894961 title "Learning Protein Folding Energy Functions" @default.
- W2025894961 cites W1979648751 @default.
- W2025894961 cites W1985514943 @default.
- W2025894961 cites W2045777307 @default.
- W2025894961 cites W2047221353 @default.
- W2025894961 cites W2069317438 @default.
- W2025894961 cites W2098138211 @default.
- W2025894961 cites W2108862644 @default.
- W2025894961 cites W2121702291 @default.
- W2025894961 cites W2127176025 @default.
- W2025894961 cites W2135815512 @default.
- W2025894961 cites W2136567909 @default.
- W2025894961 cites W2139281871 @default.
- W2025894961 cites W2156909104 @default.
- W2025894961 cites W2161151688 @default.
- W2025894961 cites W2170471837 @default.
- W2025894961 doi "https://doi.org/10.1109/icdm.2011.88" @default.
- W2025894961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4192713" @default.
- W2025894961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25311546" @default.
- W2025894961 hasPublicationYear "2011" @default.
- W2025894961 type Work @default.
- W2025894961 sameAs 2025894961 @default.
- W2025894961 citedByCount "4" @default.
- W2025894961 countsByYear W20258949612015 @default.
- W2025894961 countsByYear W20258949612019 @default.
- W2025894961 countsByYear W20258949612023 @default.
- W2025894961 crossrefType "proceedings-article" @default.
- W2025894961 hasAuthorship W2025894961A5005255629 @default.
- W2025894961 hasAuthorship W2025894961A5010808261 @default.
- W2025894961 hasAuthorship W2025894961A5011303933 @default.
- W2025894961 hasAuthorship W2025894961A5037119402 @default.
- W2025894961 hasAuthorship W2025894961A5040719512 @default.
- W2025894961 hasAuthorship W2025894961A5071397525 @default.
- W2025894961 hasAuthorship W2025894961A5074570646 @default.
- W2025894961 hasAuthorship W2025894961A5084686197 @default.
- W2025894961 hasBestOaLocation W20258949612 @default.
- W2025894961 hasConcept C105795698 @default.
- W2025894961 hasConcept C114614502 @default.
- W2025894961 hasConcept C119857082 @default.
- W2025894961 hasConcept C121332964 @default.
- W2025894961 hasConcept C12267149 @default.
- W2025894961 hasConcept C126255220 @default.
- W2025894961 hasConcept C154945302 @default.
- W2025894961 hasConcept C164226766 @default.
- W2025894961 hasConcept C186370098 @default.
- W2025894961 hasConcept C189430467 @default.
- W2025894961 hasConcept C204328495 @default.
- W2025894961 hasConcept C33923547 @default.
- W2025894961 hasConcept C41008148 @default.
- W2025894961 hasConcept C46141821 @default.
- W2025894961 hasConcept C86037889 @default.
- W2025894961 hasConceptScore W2025894961C105795698 @default.
- W2025894961 hasConceptScore W2025894961C114614502 @default.
- W2025894961 hasConceptScore W2025894961C119857082 @default.
- W2025894961 hasConceptScore W2025894961C121332964 @default.
- W2025894961 hasConceptScore W2025894961C12267149 @default.
- W2025894961 hasConceptScore W2025894961C126255220 @default.
- W2025894961 hasConceptScore W2025894961C154945302 @default.
- W2025894961 hasConceptScore W2025894961C164226766 @default.
- W2025894961 hasConceptScore W2025894961C186370098 @default.
- W2025894961 hasConceptScore W2025894961C189430467 @default.
- W2025894961 hasConceptScore W2025894961C204328495 @default.
- W2025894961 hasConceptScore W2025894961C33923547 @default.
- W2025894961 hasConceptScore W2025894961C41008148 @default.
- W2025894961 hasConceptScore W2025894961C46141821 @default.
- W2025894961 hasConceptScore W2025894961C86037889 @default.
- W2025894961 hasLocation W20258949611 @default.
- W2025894961 hasLocation W20258949612 @default.
- W2025894961 hasLocation W20258949613 @default.
- W2025894961 hasLocation W20258949614 @default.
- W2025894961 hasLocation W20258949615 @default.
- W2025894961 hasOpenAccess W2025894961 @default.
- W2025894961 hasPrimaryLocation W20258949611 @default.
- W2025894961 hasRelatedWork W1786507113 @default.
- W2025894961 hasRelatedWork W2138488530 @default.
- W2025894961 hasRelatedWork W2293317945 @default.
- W2025894961 hasRelatedWork W2499321295 @default.
- W2025894961 hasRelatedWork W2572749905 @default.
- W2025894961 hasRelatedWork W2963493716 @default.
- W2025894961 hasRelatedWork W3127142483 @default.
- W2025894961 hasRelatedWork W4297665600 @default.
- W2025894961 hasRelatedWork W4318960487 @default.
- W2025894961 hasRelatedWork W4323349240 @default.
- W2025894961 isParatext "false" @default.
- W2025894961 isRetracted "false" @default.
- W2025894961 magId "2025894961" @default.
- W2025894961 workType "article" @default.