Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025897284> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2025897284 endingPage "426" @default.
- W2025897284 startingPage "426" @default.
- W2025897284 abstract "Introduction: Prescription of palivizumab varies throughout the UK. Concern regarding the high price of RSV prophylaxis compared to possible savings from preventing an admission is cited as a reason to restrict palivizumab prescription. We report a method for minimising drug costs, achieving a 16% reduction with no adverse impact on clinical effectiveness. Aims: To tightly coordinate the delivery of palivizumab prophylaxis, reducing drug wastage by cohorting and vial sharing. Methods: We identified barriers to efficient cohorting through audit of previous experience and appointed a trainee to coordinate a programme of clinics to deliver RSV prophylaxis. Prior to the start of the season we agreed referral criteria, improved the referral process and sent explanatory letters to parents and general practitioners. Initial referrals were split into three groups who attended on consecutive afternoons for their first dose. Infants who were inpatients for part or all of the season were identified and dosed along with main cohorts. Infants continued to be referred throughout the season and new cohorts were created, timed to join a main cohort after the first dose where possible. Non-attenders were contacted by the coordinator and re-appointed to join another group. Results: We began with three cohorts and ended with eight without compromising dosage intervals. We reduced drug wastage by 14% with a monetary saving of 16%. Over the whole season we dispensed 34,300mg and delivered 32,570mg in 356 doses to 114 patients at a total drug cost of £220,847, discarding only 1,730 mg (5%). Without vial sharing we would have dispensed 39,900mg and spent a further £41,527. Five patients were hospitalised with RSV (4.4%) which is in line with the published efficacy of palivizumab prophylaxis. Conclusions: We have minimised drug costs effectively through strict cohorting and vial sharing, positively contributing to the cost-benefit analysis of RSV prophylaxis." @default.
- W2025897284 created "2016-06-24" @default.
- W2025897284 creator A5000422166 @default.
- W2025897284 creator A5024879431 @default.
- W2025897284 creator A5054640800 @default.
- W2025897284 date "2005-08-01" @default.
- W2025897284 modified "2023-09-25" @default.
- W2025897284 title "420 Cost Minimisation of Respiratory Syncitial Virus Prophylaxis with Palivizumab" @default.
- W2025897284 doi "https://doi.org/10.1203/00006450-200508000-00449" @default.
- W2025897284 hasPublicationYear "2005" @default.
- W2025897284 type Work @default.
- W2025897284 sameAs 2025897284 @default.
- W2025897284 citedByCount "0" @default.
- W2025897284 crossrefType "journal-article" @default.
- W2025897284 hasAuthorship W2025897284A5000422166 @default.
- W2025897284 hasAuthorship W2025897284A5024879431 @default.
- W2025897284 hasAuthorship W2025897284A5054640800 @default.
- W2025897284 hasBestOaLocation W20258972841 @default.
- W2025897284 hasConcept C104863432 @default.
- W2025897284 hasConcept C126322002 @default.
- W2025897284 hasConcept C142724271 @default.
- W2025897284 hasConcept C147789679 @default.
- W2025897284 hasConcept C159110408 @default.
- W2025897284 hasConcept C162324750 @default.
- W2025897284 hasConcept C185592680 @default.
- W2025897284 hasConcept C187212893 @default.
- W2025897284 hasConcept C187736073 @default.
- W2025897284 hasConcept C194828623 @default.
- W2025897284 hasConcept C199521495 @default.
- W2025897284 hasConcept C2426938 @default.
- W2025897284 hasConcept C2776135927 @default.
- W2025897284 hasConcept C2778644256 @default.
- W2025897284 hasConcept C512399662 @default.
- W2025897284 hasConcept C534529494 @default.
- W2025897284 hasConcept C71924100 @default.
- W2025897284 hasConcept C72092618 @default.
- W2025897284 hasConcept C72563966 @default.
- W2025897284 hasConcept C86941820 @default.
- W2025897284 hasConceptScore W2025897284C104863432 @default.
- W2025897284 hasConceptScore W2025897284C126322002 @default.
- W2025897284 hasConceptScore W2025897284C142724271 @default.
- W2025897284 hasConceptScore W2025897284C147789679 @default.
- W2025897284 hasConceptScore W2025897284C159110408 @default.
- W2025897284 hasConceptScore W2025897284C162324750 @default.
- W2025897284 hasConceptScore W2025897284C185592680 @default.
- W2025897284 hasConceptScore W2025897284C187212893 @default.
- W2025897284 hasConceptScore W2025897284C187736073 @default.
- W2025897284 hasConceptScore W2025897284C194828623 @default.
- W2025897284 hasConceptScore W2025897284C199521495 @default.
- W2025897284 hasConceptScore W2025897284C2426938 @default.
- W2025897284 hasConceptScore W2025897284C2776135927 @default.
- W2025897284 hasConceptScore W2025897284C2778644256 @default.
- W2025897284 hasConceptScore W2025897284C512399662 @default.
- W2025897284 hasConceptScore W2025897284C534529494 @default.
- W2025897284 hasConceptScore W2025897284C71924100 @default.
- W2025897284 hasConceptScore W2025897284C72092618 @default.
- W2025897284 hasConceptScore W2025897284C72563966 @default.
- W2025897284 hasConceptScore W2025897284C86941820 @default.
- W2025897284 hasIssue "2" @default.
- W2025897284 hasLocation W20258972841 @default.
- W2025897284 hasOpenAccess W2025897284 @default.
- W2025897284 hasPrimaryLocation W20258972841 @default.
- W2025897284 hasRelatedWork W2042489430 @default.
- W2025897284 hasRelatedWork W2135000708 @default.
- W2025897284 hasRelatedWork W2161557415 @default.
- W2025897284 hasRelatedWork W2169732003 @default.
- W2025897284 hasRelatedWork W2351564920 @default.
- W2025897284 hasRelatedWork W2413509084 @default.
- W2025897284 hasRelatedWork W2894977212 @default.
- W2025897284 hasRelatedWork W2903630145 @default.
- W2025897284 hasRelatedWork W2911654862 @default.
- W2025897284 hasRelatedWork W3096494825 @default.
- W2025897284 hasVolume "58" @default.
- W2025897284 isParatext "false" @default.
- W2025897284 isRetracted "false" @default.
- W2025897284 magId "2025897284" @default.
- W2025897284 workType "article" @default.