Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025931153> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2025931153 endingPage "341" @default.
- W2025931153 startingPage "337" @default.
- W2025931153 abstract "Brain aging is characterized by functional deterioration across multiple systems, associated to a progressive decay of neural plasticity. Here, we explored environmental enrichment (EE), a condition of enhanced sensory-motor and cognitive stimulation, as a strategy to restore plasticity processes in the old brain. Visual system is one of the paradigmatic models for studying experience-dependent plasticity. While reducing input from one eye through monocular deprivation induces a marked ocular dominance (OD) shift of neurons in the primary visual cortex during development, the same manipulation is totally ineffective after the closure of the critical period. We show that EE is able to reactivate OD plasticity in the visual cortex of aging rats, as assessed with both visual-evoked potentials and single-unit recordings. A marked reduction in intracortical GABAergic inhibition and a remodeling of extracellular matrix accompany this effect. The non-invasive nature of EE makes this paradigm eligible for human application." @default.
- W2025931153 created "2016-06-24" @default.
- W2025931153 creator A5043647281 @default.
- W2025931153 creator A5062254101 @default.
- W2025931153 creator A5063679344 @default.
- W2025931153 creator A5069210075 @default.
- W2025931153 creator A5080922013 @default.
- W2025931153 date "2012-04-01" @default.
- W2025931153 modified "2023-10-03" @default.
- W2025931153 title "A rich environmental experience reactivates visual cortex plasticity in aged rats" @default.
- W2025931153 cites W1973311433 @default.
- W2025931153 cites W1988463220 @default.
- W2025931153 cites W1988993555 @default.
- W2025931153 cites W1992842030 @default.
- W2025931153 cites W2006129024 @default.
- W2025931153 cites W2043860721 @default.
- W2025931153 cites W2065104375 @default.
- W2025931153 cites W2074562018 @default.
- W2025931153 cites W2082407289 @default.
- W2025931153 cites W2091187766 @default.
- W2025931153 cites W2154908600 @default.
- W2025931153 cites W2169520831 @default.
- W2025931153 cites W2170883319 @default.
- W2025931153 doi "https://doi.org/10.1016/j.exger.2012.01.007" @default.
- W2025931153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22329907" @default.
- W2025931153 hasPublicationYear "2012" @default.
- W2025931153 type Work @default.
- W2025931153 sameAs 2025931153 @default.
- W2025931153 citedByCount "41" @default.
- W2025931153 countsByYear W20259311532012 @default.
- W2025931153 countsByYear W20259311532013 @default.
- W2025931153 countsByYear W20259311532014 @default.
- W2025931153 countsByYear W20259311532015 @default.
- W2025931153 countsByYear W20259311532016 @default.
- W2025931153 countsByYear W20259311532017 @default.
- W2025931153 countsByYear W20259311532018 @default.
- W2025931153 countsByYear W20259311532019 @default.
- W2025931153 countsByYear W20259311532020 @default.
- W2025931153 countsByYear W20259311532021 @default.
- W2025931153 countsByYear W20259311532022 @default.
- W2025931153 crossrefType "journal-article" @default.
- W2025931153 hasAuthorship W2025931153A5043647281 @default.
- W2025931153 hasAuthorship W2025931153A5062254101 @default.
- W2025931153 hasAuthorship W2025931153A5063679344 @default.
- W2025931153 hasAuthorship W2025931153A5069210075 @default.
- W2025931153 hasAuthorship W2025931153A5080922013 @default.
- W2025931153 hasConcept C121332964 @default.
- W2025931153 hasConcept C129987498 @default.
- W2025931153 hasConcept C15744967 @default.
- W2025931153 hasConcept C169760540 @default.
- W2025931153 hasConcept C183836922 @default.
- W2025931153 hasConcept C2777348757 @default.
- W2025931153 hasConcept C2779083617 @default.
- W2025931153 hasConcept C2779345533 @default.
- W2025931153 hasConcept C47611674 @default.
- W2025931153 hasConcept C53927964 @default.
- W2025931153 hasConcept C6084040 @default.
- W2025931153 hasConcept C79186407 @default.
- W2025931153 hasConcept C86803240 @default.
- W2025931153 hasConcept C94487597 @default.
- W2025931153 hasConcept C97355855 @default.
- W2025931153 hasConceptScore W2025931153C121332964 @default.
- W2025931153 hasConceptScore W2025931153C129987498 @default.
- W2025931153 hasConceptScore W2025931153C15744967 @default.
- W2025931153 hasConceptScore W2025931153C169760540 @default.
- W2025931153 hasConceptScore W2025931153C183836922 @default.
- W2025931153 hasConceptScore W2025931153C2777348757 @default.
- W2025931153 hasConceptScore W2025931153C2779083617 @default.
- W2025931153 hasConceptScore W2025931153C2779345533 @default.
- W2025931153 hasConceptScore W2025931153C47611674 @default.
- W2025931153 hasConceptScore W2025931153C53927964 @default.
- W2025931153 hasConceptScore W2025931153C6084040 @default.
- W2025931153 hasConceptScore W2025931153C79186407 @default.
- W2025931153 hasConceptScore W2025931153C86803240 @default.
- W2025931153 hasConceptScore W2025931153C94487597 @default.
- W2025931153 hasConceptScore W2025931153C97355855 @default.
- W2025931153 hasIssue "4" @default.
- W2025931153 hasLocation W20259311531 @default.
- W2025931153 hasLocation W20259311532 @default.
- W2025931153 hasOpenAccess W2025931153 @default.
- W2025931153 hasPrimaryLocation W20259311531 @default.
- W2025931153 hasRelatedWork W1971604198 @default.
- W2025931153 hasRelatedWork W1998529665 @default.
- W2025931153 hasRelatedWork W2025931153 @default.
- W2025931153 hasRelatedWork W2036970711 @default.
- W2025931153 hasRelatedWork W2091187766 @default.
- W2025931153 hasRelatedWork W2097532290 @default.
- W2025931153 hasRelatedWork W2165703503 @default.
- W2025931153 hasRelatedWork W2576200020 @default.
- W2025931153 hasRelatedWork W2799533278 @default.
- W2025931153 hasRelatedWork W3197467040 @default.
- W2025931153 hasVolume "47" @default.
- W2025931153 isParatext "false" @default.
- W2025931153 isRetracted "false" @default.
- W2025931153 magId "2025931153" @default.
- W2025931153 workType "article" @default.