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- W2025964188 abstract "A series of 6-hydroxy-7-thioether and 6-thioether-7-hydroxy derivatives of commercially available petroselinic acid and 5-hydroxy-6-thioether derivatives of fatty acids containing an aromatic moiety were synthesized. Several of the compounds have exhibited SRS-A antagonist (eg, 5, 10)/agonist (eg, 34, 35) activity. Compound 5 antagonized SRS-A-induced contractions of the isolated guinea pig ileum with IC50 = 0.09 μM." @default.
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- W2025964188 date "1993-01-01" @default.
- W2025964188 modified "2023-09-26" @default.
- W2025964188 title "Synthesis and biological properties of hydroxythioether fatty acids related to leukotrienes: Antagonists and agonists of slow-reacting substance of anaphylaxis (SRS-A)" @default.
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- W2025964188 doi "https://doi.org/10.1016/0223-5234(93)90073-n" @default.
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