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• W2025969752 abstract "We have cloned and sequenced transcripts from the X- and Y-linked zinc-finger genes ZFX and ZFY respectively and discuss a possible mechanism of post-transcriptional control by which these genes can be widely expressed but translated in only specific tissues. We report the identification of a novel 3'UTR (untranslated region) present in ZFY which is highly conserved among primates and contains a series of motifs implicated as mRNA instability determinants. These sequences can be substantially removed by polyadenylation directed from consensus (AATAAA) and non-consensus (AATATAAA) sequences in adult testis. The DNA-binding domains of the ZFY and ZFX proteins are compared using present models for zinc-finger/DNA interactions. Additionally, the genomic organisation of the ZFY coding sequence is presented as compared to that of ZFX." @default.
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• W2025969752 date "1991-05-25" @default.
• W2025969752 modified "2023-10-16" @default.
• W2025969752 title "Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY" @default.
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• W2025969752 doi "https://doi.org/10.1093/nar/19.10.2579" @default.
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