Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025989810> ?p ?o ?g. }
- W2025989810 endingPage "11" @default.
- W2025989810 startingPage "1" @default.
- W2025989810 abstract "In a study of the effects of severe chronic ethanol intoxication and withdrawal, immunoelectrophoretic measurements were made of the specific nervous system proteins D1, D2, D3, synaptin, 14-3-2, and glutamine synthetase in the brain. During chronic ethanol intoxication, none of these proteins deviated significantly from normal values, so the structural background for neuronal function was not measurably disturbed by any toxic effect of ethanol. However, during the ethanol withdrawal reaction, the specific concentrations of neuronal proteins D1, D2, 14-3-2, and synaptin were increased, and they subsequently normalized. D3 in brain and D2 in cerebrospinal fluid were decreased and subsequently normalized. When the neuronal localization and the possible function of these proteins are considered, the results may be interpreted as indicating an increased synthesis of neuronal synapses during the ethanol withdrawal reaction accompanied by a transient halt in synaptic decomposition. No changes occurred in the glial marker glutamine synthetase, and thus the measured changes in specific brain protein concentrations apparently reflect the structural dynamics of establishing the substrate for the functional neuronal hyperactivity constituting the ethanol withdrawal reaction." @default.
- W2025989810 created "2016-06-24" @default.
- W2025989810 creator A5049188860 @default.
- W2025989810 creator A5069982622 @default.
- W2025989810 date "1980-09-01" @default.
- W2025989810 modified "2023-09-27" @default.
- W2025989810 title "Specific brain proteins during severe ethanol intoxication and withdrawal in the rat" @default.
- W2025989810 cites W1480181846 @default.
- W2025989810 cites W1775749144 @default.
- W2025989810 cites W1964292943 @default.
- W2025989810 cites W1967865367 @default.
- W2025989810 cites W1968085365 @default.
- W2025989810 cites W1971699057 @default.
- W2025989810 cites W1972010705 @default.
- W2025989810 cites W1978013837 @default.
- W2025989810 cites W1982180324 @default.
- W2025989810 cites W1984089779 @default.
- W2025989810 cites W1987080089 @default.
- W2025989810 cites W1990986783 @default.
- W2025989810 cites W1992043671 @default.
- W2025989810 cites W2002983094 @default.
- W2025989810 cites W2004445728 @default.
- W2025989810 cites W2005814409 @default.
- W2025989810 cites W2009656535 @default.
- W2025989810 cites W2012463091 @default.
- W2025989810 cites W2013815042 @default.
- W2025989810 cites W2014422638 @default.
- W2025989810 cites W2018267333 @default.
- W2025989810 cites W2020163557 @default.
- W2025989810 cites W2022651316 @default.
- W2025989810 cites W2027244585 @default.
- W2025989810 cites W2040706591 @default.
- W2025989810 cites W2049646574 @default.
- W2025989810 cites W2055381700 @default.
- W2025989810 cites W2055472365 @default.
- W2025989810 cites W2059829197 @default.
- W2025989810 cites W2066984663 @default.
- W2025989810 cites W2068185857 @default.
- W2025989810 cites W2088334621 @default.
- W2025989810 cites W2094924723 @default.
- W2025989810 cites W2102131116 @default.
- W2025989810 cites W2132443705 @default.
- W2025989810 cites W2132653530 @default.
- W2025989810 cites W2326911653 @default.
- W2025989810 cites W2419002997 @default.
- W2025989810 cites W4229712605 @default.
- W2025989810 doi "https://doi.org/10.1016/0165-1781(80)90042-6" @default.
- W2025989810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6108585" @default.
- W2025989810 hasPublicationYear "1980" @default.
- W2025989810 type Work @default.
- W2025989810 sameAs 2025989810 @default.
- W2025989810 citedByCount "23" @default.
- W2025989810 countsByYear W20259898102020 @default.
- W2025989810 crossrefType "journal-article" @default.
- W2025989810 hasAuthorship W2025989810A5049188860 @default.
- W2025989810 hasAuthorship W2025989810A5069982622 @default.
- W2025989810 hasConcept C126322002 @default.
- W2025989810 hasConcept C134018914 @default.
- W2025989810 hasConcept C169760540 @default.
- W2025989810 hasConcept C185592680 @default.
- W2025989810 hasConcept C2779289688 @default.
- W2025989810 hasConcept C2779349466 @default.
- W2025989810 hasConcept C2779651940 @default.
- W2025989810 hasConcept C2780161600 @default.
- W2025989810 hasConcept C3018390542 @default.
- W2025989810 hasConcept C515207424 @default.
- W2025989810 hasConcept C529278444 @default.
- W2025989810 hasConcept C55493867 @default.
- W2025989810 hasConcept C71924100 @default.
- W2025989810 hasConcept C86803240 @default.
- W2025989810 hasConceptScore W2025989810C126322002 @default.
- W2025989810 hasConceptScore W2025989810C134018914 @default.
- W2025989810 hasConceptScore W2025989810C169760540 @default.
- W2025989810 hasConceptScore W2025989810C185592680 @default.
- W2025989810 hasConceptScore W2025989810C2779289688 @default.
- W2025989810 hasConceptScore W2025989810C2779349466 @default.
- W2025989810 hasConceptScore W2025989810C2779651940 @default.
- W2025989810 hasConceptScore W2025989810C2780161600 @default.
- W2025989810 hasConceptScore W2025989810C3018390542 @default.
- W2025989810 hasConceptScore W2025989810C515207424 @default.
- W2025989810 hasConceptScore W2025989810C529278444 @default.
- W2025989810 hasConceptScore W2025989810C55493867 @default.
- W2025989810 hasConceptScore W2025989810C71924100 @default.
- W2025989810 hasConceptScore W2025989810C86803240 @default.
- W2025989810 hasIssue "1" @default.
- W2025989810 hasLocation W20259898101 @default.
- W2025989810 hasLocation W20259898102 @default.
- W2025989810 hasOpenAccess W2025989810 @default.
- W2025989810 hasPrimaryLocation W20259898101 @default.
- W2025989810 hasRelatedWork W1535914835 @default.
- W2025989810 hasRelatedWork W1600401047 @default.
- W2025989810 hasRelatedWork W1993404602 @default.
- W2025989810 hasRelatedWork W1999877847 @default.
- W2025989810 hasRelatedWork W2008264923 @default.
- W2025989810 hasRelatedWork W2056458707 @default.
- W2025989810 hasRelatedWork W2115629088 @default.
- W2025989810 hasRelatedWork W2153965615 @default.
- W2025989810 hasRelatedWork W2155854266 @default.