Matches in SemOpenAlex for { <https://semopenalex.org/work/W2025998052> ?p ?o ?g. }
- W2025998052 endingPage "129" @default.
- W2025998052 startingPage "119" @default.
- W2025998052 abstract "One of the most important threats to the salmonid aquaculture industry is infection caused by novirhabdoviruses such as infectious haematopoietic necrosis virus (IHNV) or viral haemorrhagic septicaemia virus (VHSV). Using reverse genetics, an avirulent recombinant rIHNV-Gvhsv GFP strain was generated, which was able to replicate as effectively as wild type IHNV in a fish cell line and in macrophages. Although this recombinant virus induced protective responses against IHNV and VHSV, the response did not involve the production of antibodies or modulate the expression of some antiviral genes. To determine the immune mechanisms underlying the protection conferred by the rIHNV-Gvhsv GFP virus, different immune parameters (NO production, respiratory burst activity and the induction of apoptosis) were assessed in the macrophage population. The results obtained in the present work may indicate that the Nv protein could be important in the modulation of NO and ROS production. rIHNV-Gvhsv GFP did not appear to have a clear effect on nitric oxide production or apoptosis. However, an increased respiratory burst activity (with levels induced by the recombinant virus significantly higher than the levels induced by the wild type virus), suggests a stimulation of the macrophage population, which could be related to the protection against virulent viruses." @default.
- W2025998052 created "2016-06-24" @default.
- W2025998052 creator A5006562505 @default.
- W2025998052 creator A5035725666 @default.
- W2025998052 creator A5059682637 @default.
- W2025998052 creator A5061485833 @default.
- W2025998052 creator A5079324448 @default.
- W2025998052 date "2011-03-01" @default.
- W2025998052 modified "2023-09-25" @default.
- W2025998052 title "Interaction of the attenuated recombinant rIHNV-Gvhsv GFP virus with macrophages from rainbow trout (Oncorhynchus mykiss)" @default.
- W2025998052 cites W1548343108 @default.
- W2025998052 cites W1589333316 @default.
- W2025998052 cites W1876476959 @default.
- W2025998052 cites W1975982125 @default.
- W2025998052 cites W1977110453 @default.
- W2025998052 cites W1979813052 @default.
- W2025998052 cites W1983889779 @default.
- W2025998052 cites W1985968246 @default.
- W2025998052 cites W1989064148 @default.
- W2025998052 cites W1989394243 @default.
- W2025998052 cites W1990711825 @default.
- W2025998052 cites W1994821644 @default.
- W2025998052 cites W1996155138 @default.
- W2025998052 cites W2006485666 @default.
- W2025998052 cites W2007489407 @default.
- W2025998052 cites W2008013204 @default.
- W2025998052 cites W2010351227 @default.
- W2025998052 cites W2012744796 @default.
- W2025998052 cites W2013346825 @default.
- W2025998052 cites W2015761674 @default.
- W2025998052 cites W2015853781 @default.
- W2025998052 cites W2019489183 @default.
- W2025998052 cites W2020148332 @default.
- W2025998052 cites W2022167422 @default.
- W2025998052 cites W2025910617 @default.
- W2025998052 cites W2028612580 @default.
- W2025998052 cites W2035409635 @default.
- W2025998052 cites W2038421834 @default.
- W2025998052 cites W2055221354 @default.
- W2025998052 cites W2056686888 @default.
- W2025998052 cites W2057786547 @default.
- W2025998052 cites W2060660052 @default.
- W2025998052 cites W2061683009 @default.
- W2025998052 cites W2063828696 @default.
- W2025998052 cites W2066027429 @default.
- W2025998052 cites W2071649344 @default.
- W2025998052 cites W2073132923 @default.
- W2025998052 cites W2074352518 @default.
- W2025998052 cites W2075375841 @default.
- W2025998052 cites W2084692378 @default.
- W2025998052 cites W2085628741 @default.
- W2025998052 cites W2092359155 @default.
- W2025998052 cites W2095870354 @default.
- W2025998052 cites W2109541706 @default.
- W2025998052 cites W2109883473 @default.
- W2025998052 cites W2121336765 @default.
- W2025998052 cites W2122299206 @default.
- W2025998052 cites W2125337655 @default.
- W2025998052 cites W2132522063 @default.
- W2025998052 cites W2136463851 @default.
- W2025998052 cites W2144882771 @default.
- W2025998052 cites W2146766320 @default.
- W2025998052 cites W2151004253 @default.
- W2025998052 cites W2152987047 @default.
- W2025998052 cites W2160490904 @default.
- W2025998052 cites W2162903693 @default.
- W2025998052 cites W2163064968 @default.
- W2025998052 cites W2167655650 @default.
- W2025998052 cites W2170520701 @default.
- W2025998052 cites W2171275289 @default.
- W2025998052 cites W2171601543 @default.
- W2025998052 doi "https://doi.org/10.1016/j.vetimm.2010.12.001" @default.
- W2025998052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21185087" @default.
- W2025998052 hasPublicationYear "2011" @default.
- W2025998052 type Work @default.
- W2025998052 sameAs 2025998052 @default.
- W2025998052 citedByCount "10" @default.
- W2025998052 countsByYear W20259980522013 @default.
- W2025998052 countsByYear W20259980522014 @default.
- W2025998052 countsByYear W20259980522015 @default.
- W2025998052 countsByYear W20259980522019 @default.
- W2025998052 countsByYear W20259980522020 @default.
- W2025998052 countsByYear W20259980522021 @default.
- W2025998052 crossrefType "journal-article" @default.
- W2025998052 hasAuthorship W2025998052A5006562505 @default.
- W2025998052 hasAuthorship W2025998052A5035725666 @default.
- W2025998052 hasAuthorship W2025998052A5059682637 @default.
- W2025998052 hasAuthorship W2025998052A5061485833 @default.
- W2025998052 hasAuthorship W2025998052A5079324448 @default.
- W2025998052 hasBestOaLocation W20259980523 @default.
- W2025998052 hasConcept C104317684 @default.
- W2025998052 hasConcept C144024400 @default.
- W2025998052 hasConcept C149923435 @default.
- W2025998052 hasConcept C159047783 @default.
- W2025998052 hasConcept C203014093 @default.
- W2025998052 hasConcept C2522874641 @default.
- W2025998052 hasConcept C2778966499 @default.
- W2025998052 hasConcept C2908647359 @default.