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- W2026017156 abstract "A method is described for the quantitative determination of endotoxins in blood. The method is based upon the endotoxin-dependent activation of a proenzyme present in Limulus amebocyte lysate. This activated enzyme is measured by using the chromogenic substrate S 2422. Inhibitors and activated coagulation factors possibly interfering in the assay are removed by dilution and boiling. The method has been proven to be fast (2.5 h), sensitive and reproducible with a detection limit of 10 ng/l. Preliminary results comparing the results of blood cultures with the endotoxin assay indicate a good correlation." @default.
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- W2026017156 date "1981-10-01" @default.
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- W2026017156 title "Quantitative endotoxin determination in blood with a chromogenic substrate" @default.
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- W2026017156 doi "https://doi.org/10.1016/0009-8981(81)90169-8" @default.
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