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- W2026054723 abstract "Based on our previously described synthetic strategy for bengamide E, a natural product of marine origin with antitumor activity, a small library of analogues modified at the terminal olefinic position was generated with the objective of investigating the effect of structural modifications on antitumor properties. Biological evaluation of these analogues, consisting of IC50 determinations against various tumor cell lines, revealed important aspects with respect to the structural requirements of this olefinic position for activity. Interestingly, the analogue possessing a cyclopentyl group displayed greater potency than the parent bengamide E, representing a key finding upon which to base further investigations into the design of new analogues with promising biological activities." @default.
- W2026054723 created "2016-06-24" @default.
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- W2026054723 creator A5034075531 @default.
- W2026054723 creator A5056568607 @default.
- W2026054723 date "2013-03-19" @default.
- W2026054723 modified "2023-10-18" @default.
- W2026054723 title "An Array of Bengamide E Analogues Modified at the Terminal Olefinic Position: Synthesis and Antitumor Properties" @default.
- W2026054723 cites W172067623 @default.
- W2026054723 cites W1966522252 @default.
- W2026054723 cites W1968157972 @default.
- W2026054723 cites W1973458368 @default.
- W2026054723 cites W1978181742 @default.
- W2026054723 cites W1979805133 @default.
- W2026054723 cites W1982675522 @default.
- W2026054723 cites W1982750715 @default.
- W2026054723 cites W1984610255 @default.
- W2026054723 cites W1985727888 @default.
- W2026054723 cites W1987651578 @default.
- W2026054723 cites W1991737092 @default.
- W2026054723 cites W1992688100 @default.
- W2026054723 cites W1998913896 @default.
- W2026054723 cites W1999685593 @default.
- W2026054723 cites W2002228578 @default.
- W2026054723 cites W2003862801 @default.
- W2026054723 cites W2003867194 @default.
- W2026054723 cites W2008552379 @default.
- W2026054723 cites W2010435021 @default.
- W2026054723 cites W2015404405 @default.
- W2026054723 cites W2018416180 @default.
- W2026054723 cites W2019943090 @default.
- W2026054723 cites W2021347570 @default.
- W2026054723 cites W2021960494 @default.
- W2026054723 cites W2024536147 @default.
- W2026054723 cites W2034770513 @default.
- W2026054723 cites W2038125376 @default.
- W2026054723 cites W2039427435 @default.
- W2026054723 cites W2039792881 @default.
- W2026054723 cites W2041161580 @default.
- W2026054723 cites W2050284673 @default.
- W2026054723 cites W2055994794 @default.
- W2026054723 cites W2060494402 @default.
- W2026054723 cites W2062927139 @default.
- W2026054723 cites W2064823771 @default.
- W2026054723 cites W2065010990 @default.
- W2026054723 cites W2066088507 @default.
- W2026054723 cites W2068669929 @default.
- W2026054723 cites W2069763602 @default.
- W2026054723 cites W2071214593 @default.
- W2026054723 cites W2072920353 @default.
- W2026054723 cites W2074836458 @default.
- W2026054723 cites W2076826594 @default.
- W2026054723 cites W2083613735 @default.
- W2026054723 cites W2085785716 @default.
- W2026054723 cites W2087704160 @default.
- W2026054723 cites W2091246008 @default.
- W2026054723 cites W2092483187 @default.
- W2026054723 cites W2092781044 @default.
- W2026054723 cites W2093317402 @default.
- W2026054723 cites W2094659953 @default.
- W2026054723 cites W2095160245 @default.
- W2026054723 cites W2107257265 @default.
- W2026054723 cites W2108494831 @default.
- W2026054723 cites W2113246465 @default.
- W2026054723 cites W2114756704 @default.
- W2026054723 cites W2114918609 @default.
- W2026054723 cites W2125271512 @default.
- W2026054723 cites W2126014249 @default.
- W2026054723 cites W2134262362 @default.
- W2026054723 cites W2135193488 @default.
- W2026054723 cites W2139037466 @default.
- W2026054723 cites W2148192846 @default.
- W2026054723 cites W2148548617 @default.
- W2026054723 cites W2151284087 @default.
- W2026054723 cites W2156961652 @default.
- W2026054723 cites W2158705213 @default.
- W2026054723 cites W2159068988 @default.
- W2026054723 cites W2162444913 @default.
- W2026054723 cites W2171409436 @default.
- W2026054723 cites W2949221551 @default.
- W2026054723 cites W2949461158 @default.
- W2026054723 cites W2949949317 @default.
- W2026054723 cites W2950057496 @default.
- W2026054723 cites W2950395401 @default.
- W2026054723 cites W2951157344 @default.
- W2026054723 cites W2951369717 @default.
- W2026054723 cites W2951725978 @default.
- W2026054723 cites W2953342415 @default.
- W2026054723 cites W4232792380 @default.
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- W2026054723 doi "https://doi.org/10.1002/cmdc.201300033" @default.
- W2026054723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23512621" @default.
- W2026054723 hasPublicationYear "2013" @default.
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