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• W2026062012 abstract "No AccessJournal of UrologyAdult Urology: Outcomes/Epidemiology/Socioeconomics1 Jan 2005HEALTH RELATED QUALITY OF LIFE BEFORE AND AFTER LAPAROSCOPIC RADICAL PROSTATECTOMY RICHARD E. LINK, LI-MING SU, WENDY SULLIVAN, SAM B. BHAYANI, and CHRISTIAN P. PAVLOVICH RICHARD E. LINKRICHARD E. LINK More articles by this author , LI-MING SULI-MING SU More articles by this author , WENDY SULLIVANWENDY SULLIVAN More articles by this author , SAM B. BHAYANISAM B. BHAYANI More articles by this author , and CHRISTIAN P. PAVLOVICHCHRISTIAN P. PAVLOVICH More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000147190.67218.1bAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The viability of laparoscopic radical prostatectomy (LRP) as a surgical treatment for prostate cancer depends on oncological and health related quality of life (HRQOL) outcomes. We present a prospective assessment of HRQOL in 122 patients before and after LRP using the validated Expanded Prostate Cancer Index Composite (EPIC) questionnaire. Materials and Methods: EPIC data were collected preoperatively, and at 3, 6 and 12 months after LRP, and all were normalized to patient preoperative baseline responses. Results: Using traditional single question responses, 93.4% of patients were continent (0 to 1 pads) at postoperative month 12. Of previously potent men who underwent bilateral nerve sparing 78.9% reported engaging in sexual intercourse within postoperative year 1. However, EPIC domain scores provided a more comprehensive assessment of functional outcomes. For the urinary incontinence subdomain, the majority of functional recovery was achieved by postoperative month 6, reaching a 74% return to baseline on average. In contrast, recovery of the sexual function subdomain continued throughout postoperative year 1 (to a mean of 64%). Recovery of sexual function was not significantly affected by age or preoperative potency status, although the extent of nerve sparing was a significant predictor of outcome (mean recovery to 75% of baseline for bilateral vs 36% for no nerve sparing at 12 months, p = 0.005). Conclusions: Nerve sparing LRP provides satisfactory first year HRQOL outcomes when assessed with a validated instrument. The time course and extent of functional recovery documented in this prospective study may prove useful for patient counseling before LRP. References 1 : Comparison of recommendations by urologists and radiation oncologists for treatment of clinically localized prostate cancer. JAMA2000; 283: 3217. Google Scholar 2 : The UCLA Prostate Cancer Index: development, reliability, and validity of a health-related quality of life measure. Med Care1998; 36: 1002. 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Google Scholar 14 : Influence of body weight and prostate volume on intraoperative, perioperative, and postoperative outcomes after radical retropubic prostatectomy. Urology2003; 61: 601. Google Scholar 15 : Health outcomes after prostatectomy or radiotherapy for prostate cancer: results from the Prostate Cancer Outcomes Study. J Natl Cancer Inst2000; 92: 1582. Google Scholar 16 : A comprehensive comparison of health-related quality-of-life following contemporary therapies for localized prostate cancer. J Clin Oncol2002; 20: 557. Google Scholar 17 : Determinants of long-term sexual health outcome after radical prostatectomy measured by a validated instrument. J Urol2003; 169: 1453. Link, Google Scholar 18 : Predicting quality of life after radical prostatectomy: results from CaPSURE. J Urol2004; 171: 703. Link, Google Scholar 19 : Laparoscopic radical prostatectomy: initial 70 cases at a U.S. university medical center. Urology2002; 60: 859. Google Scholar From the James Buchanan Brady Urological Institute, Johns Hopkins Bayview Medical Center, Baltimore, Maryland© 2005 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byLevinson A, Pavlovich C, Ward N, Link R, Mettee L and Su L (2008) Association of Surgeon Subjective Characterization of Nerve Sparing Quality With Potency Following Laparoscopic Radical ProstatectomyJournal of Urology, VOL. 179, NO. 4, (1510-1514), Online publication date: 1-Apr-2008.Pavlovich C, Trock B, Sulman A, Wagner A, Mettee L and Su L (2008) 3-Year Actuarial Biochemical Recurrence-Free Survival Following Laparoscopic Radical Prostatectomy: Experience From a Tertiary Referral Center in the United StatesJournal of Urology, VOL. 179, NO. 3, (917-922), Online publication date: 1-Mar-2008.Rogers C, Su L, Link R, Sullivan W, Wagner A and Pavlovich C (2018) Age Stratified Functional Outcomes After Laparoscopic Radical ProstatectomyJournal of Urology, VOL. 176, NO. 6, (2448-2452), Online publication date: 1-Dec-2006. Volume 173Issue 1January 2005Page: 175-179 Advertisement Copyright & Permissions© 2005 by American Urological Association, Inc.Keywordsquality of lifeprostatic neoplasmsprostatectomylaparoscopyMetricsAuthor Information RICHARD E. LINK More articles by this author LI-MING SU More articles by this author WENDY SULLIVAN More articles by this author SAM B. BHAYANI More articles by this author CHRISTIAN P. PAVLOVICH More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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