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- W2026066997 abstract "New NICE guidelines seek to improve health outcomes for individuals with chronic kidney disease. They emphasise the role of primary care in dealing with two important questions: how should we assess and reduce the risk of cardiovascular events that are present among all patients with chronic kidney disease; and how can we identify the minority of individuals who are likely to progress to advanced kidney disease (and require specialist nephrological services)?One of the most controversial issues in writing such guidelines is the definition of chronic kidney disease, which relies on the ability to estimate glomerular filtration rate (GFR). As the NICE authors recognise, the current, creatinine based formulas are woefully inadequate among the 90-95% of the population who have “normal” or “moderately impaired” kidney function (GFR >45 ml/min/1.73m2). The staging system based on GFR largely ignores other measures of kidney damage—proteinuria, for example—which are useful indicators of the risk of progression of renal …" @default.
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- W2026066997 date "2008-09-29" @default.
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- W2026066997 title "Commentary: Controversies in NICE guidance on chronic kidney disease" @default.
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- W2026066997 doi "https://doi.org/10.1136/bmj.a1793" @default.
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