Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026112468> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2026112468 abstract "This study was aimed to ascertain whether the more acidic isoforms of plasma apo A-I (A-I-1 and A-I-2) could originate in vitro from the main plasma isoform (A-I0). Apo A-I isoforms were separated by two-dimensional gel electrophoresis before and after a prolonged incubation of serum or EDTA-plasma at 37 degrees C. Incubated plasma there was a marked decrease of apo A-I0 and a concomitant linear increase of apo A-I-1 + and A-I-2. The relative content of the latter raised from 22 +/- 7% before the incubation to 60 +/- 7% after 48 h of incubation. This conversion of A-I0 was not inhibited by either pre-heating of plasma at 60 degrees C for 1 h or the addition of protease inhibitors, EDTA and p-chloromercuriphenylsulfonic acid. The conversion of apo A-I0 was not observed in isolated HDL, incubated either in the absence or in the presence of d less than 1.063 g/ml lipoproteins and lipoprotein deficient plasma, nor in plasma which had been dialyzed before being incubated at 37 degrees C. This suggests that plasma contains a low molecular weight factor capable of promoting the conversion of A-I0. The increase of the relative content of apo A-I-1 and apo A-I-2 in incubated plasma was not due to glucosylation or carbamylation of A-I0 as no radioactive glucose and urea were found to be bound to A-I. Since the conversion of apo A-I0 was prevented by the addition of an antioxidant (butylated hydroxytoluene, BHT) to the incubated plasma it is conceivable that some product of lipid peroxidation renders apo A-I0 more electronegative by reacting with some free amino groups of this peptide." @default.
- W2026112468 created "2016-06-24" @default.
- W2026112468 creator A5009626049 @default.
- W2026112468 creator A5013689619 @default.
- W2026112468 creator A5075079118 @default.
- W2026112468 date "1986-03-01" @default.
- W2026112468 modified "2023-09-25" @default.
- W2026112468 title "Changes of the main isoform of human apolipoprotein A-I following incubation of plasma" @default.
- W2026112468 cites W1516138002 @default.
- W2026112468 cites W1528298906 @default.
- W2026112468 cites W1563822976 @default.
- W2026112468 cites W1572618883 @default.
- W2026112468 cites W1606960088 @default.
- W2026112468 cites W1616616982 @default.
- W2026112468 cites W193408988 @default.
- W2026112468 cites W1966583531 @default.
- W2026112468 cites W1974540651 @default.
- W2026112468 cites W1974792057 @default.
- W2026112468 cites W1975212018 @default.
- W2026112468 cites W1985870242 @default.
- W2026112468 cites W1992613388 @default.
- W2026112468 cites W1997494070 @default.
- W2026112468 cites W2000624589 @default.
- W2026112468 cites W2001697469 @default.
- W2026112468 cites W2028947098 @default.
- W2026112468 cites W2029812497 @default.
- W2026112468 cites W2033045581 @default.
- W2026112468 cites W2033519899 @default.
- W2026112468 cites W2061704447 @default.
- W2026112468 cites W2086217328 @default.
- W2026112468 cites W2088615805 @default.
- W2026112468 cites W2094364456 @default.
- W2026112468 cites W2145417330 @default.
- W2026112468 cites W2147018338 @default.
- W2026112468 cites W2149946290 @default.
- W2026112468 cites W2162458714 @default.
- W2026112468 cites W2183954926 @default.
- W2026112468 cites W2342109182 @default.
- W2026112468 cites W1968449681 @default.
- W2026112468 doi "https://doi.org/10.1016/0021-9150(86)90119-x" @default.
- W2026112468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3083834" @default.
- W2026112468 hasPublicationYear "1986" @default.
- W2026112468 type Work @default.
- W2026112468 sameAs 2026112468 @default.
- W2026112468 citedByCount "8" @default.
- W2026112468 crossrefType "journal-article" @default.
- W2026112468 hasAuthorship W2026112468A5009626049 @default.
- W2026112468 hasAuthorship W2026112468A5013689619 @default.
- W2026112468 hasAuthorship W2026112468A5075079118 @default.
- W2026112468 hasConcept C104317684 @default.
- W2026112468 hasConcept C126322002 @default.
- W2026112468 hasConcept C134018914 @default.
- W2026112468 hasConcept C181199279 @default.
- W2026112468 hasConcept C185592680 @default.
- W2026112468 hasConcept C25642318 @default.
- W2026112468 hasConcept C2776714187 @default.
- W2026112468 hasConcept C2778163477 @default.
- W2026112468 hasConcept C2780072125 @default.
- W2026112468 hasConcept C2780365088 @default.
- W2026112468 hasConcept C43617362 @default.
- W2026112468 hasConcept C53345823 @default.
- W2026112468 hasConcept C55493867 @default.
- W2026112468 hasConcept C62746215 @default.
- W2026112468 hasConcept C71924100 @default.
- W2026112468 hasConcept C86803240 @default.
- W2026112468 hasConceptScore W2026112468C104317684 @default.
- W2026112468 hasConceptScore W2026112468C126322002 @default.
- W2026112468 hasConceptScore W2026112468C134018914 @default.
- W2026112468 hasConceptScore W2026112468C181199279 @default.
- W2026112468 hasConceptScore W2026112468C185592680 @default.
- W2026112468 hasConceptScore W2026112468C25642318 @default.
- W2026112468 hasConceptScore W2026112468C2776714187 @default.
- W2026112468 hasConceptScore W2026112468C2778163477 @default.
- W2026112468 hasConceptScore W2026112468C2780072125 @default.
- W2026112468 hasConceptScore W2026112468C2780365088 @default.
- W2026112468 hasConceptScore W2026112468C43617362 @default.
- W2026112468 hasConceptScore W2026112468C53345823 @default.
- W2026112468 hasConceptScore W2026112468C55493867 @default.
- W2026112468 hasConceptScore W2026112468C62746215 @default.
- W2026112468 hasConceptScore W2026112468C71924100 @default.
- W2026112468 hasConceptScore W2026112468C86803240 @default.
- W2026112468 hasLocation W20261124681 @default.
- W2026112468 hasLocation W20261124682 @default.
- W2026112468 hasOpenAccess W2026112468 @default.
- W2026112468 hasPrimaryLocation W20261124681 @default.
- W2026112468 hasRelatedWork W1981345773 @default.
- W2026112468 hasRelatedWork W1999568358 @default.
- W2026112468 hasRelatedWork W2017677221 @default.
- W2026112468 hasRelatedWork W2033921535 @default.
- W2026112468 hasRelatedWork W2090875163 @default.
- W2026112468 hasRelatedWork W2091911513 @default.
- W2026112468 hasRelatedWork W2114268098 @default.
- W2026112468 hasRelatedWork W2151831271 @default.
- W2026112468 hasRelatedWork W2185120011 @default.
- W2026112468 hasRelatedWork W2495016602 @default.
- W2026112468 isParatext "false" @default.
- W2026112468 isRetracted "false" @default.
- W2026112468 magId "2026112468" @default.
- W2026112468 workType "article" @default.