FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026138148> ?p ?o ?g. }

• W2026138148 endingPage "512" @default.
• W2026138148 startingPage "507" @default.
• W2026138148 abstract "In the present study we have investigated the association of three single nucleotide polymorphisms in glutathione peroxidase (GPx) genes GPX1 rs1050450 (P198L), GPX3 rs2070593 (G930A) and GPX4 rs713041 (T718C) with the risk of cerebral stroke (CS) in patients with essential hypertension (EH). A total of 667 unrelated EH patients of Russian origin, including 306 hypertensives (the EH-CS group) who suffered from CS and 361 people (the EH-CS group) who did not have cerebrovascular accidents, were enrolled in the study. The variant allele 718C of the GPX4 gene was found to be significantly associated with an increased risk of CS in hypertensive patients (odds ratio (OR) 1.53, 95% confidence interval (CI) 1.23-1.90, P(adj) = 0.0003). The prevalence of the 718TC and 718CC genotypes of the GPX4 gene was higher in the EH-CS group than the EH-alone group (OR = 2.12, 95%CI 1.42-3.16, P(adj) = 0.0018). The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant after adjusting for confounding variables such as sex, body mass index (BMI), blood pressure and antihypertensive medication use (OR = 2.18, 95%CI 1.46-3.27, P = 0.0015). Multiple logistic regression analysis did not reveal any interaction between various combinations of GPX1, GPX3 and GPX4 genotypes regarding the risk of CS in patients with EH. The study demonstrated for the first time that the C718T polymorphism in the 3'-untranslated region of the GPX4 gene could be considered as a genetic marker of susceptibility to CS in patients with EH." @default.
• W2026138148 created "2016-06-24" @default.
• W2026138148 creator A5006602845 @default.
• W2026138148 creator A5009941415 @default.
• W2026138148 creator A5020440584 @default.
• W2026138148 creator A5021926190 @default.
• W2026138148 creator A5056854844 @default.
• W2026138148 creator A5060781017 @default.
• W2026138148 creator A5071033298 @default.
• W2026138148 creator A5071801392 @default.
• W2026138148 creator A5080247489 @default.
• W2026138148 creator A5081613438 @default.
• W2026138148 date "2011-12-08" @default.
• W2026138148 modified "2023-10-10" @default.
• W2026138148 title "The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension" @default.
• W2026138148 cites W1517703574 @default.
• W2026138148 cites W1970121001 @default.
• W2026138148 cites W1971736281 @default.
• W2026138148 cites W1989496643 @default.
• W2026138148 cites W2002133471 @default.
• W2026138148 cites W2003811642 @default.
• W2026138148 cites W2005771748 @default.
• W2026138148 cites W2013915720 @default.
• W2026138148 cites W2015843046 @default.
• W2026138148 cites W2018961676 @default.
• W2026138148 cites W2031340281 @default.
• W2026138148 cites W2049327564 @default.
• W2026138148 cites W2057192944 @default.
• W2026138148 cites W2058584041 @default.
• W2026138148 cites W2063011337 @default.
• W2026138148 cites W2063860588 @default.
• W2026138148 cites W2072216099 @default.
• W2026138148 cites W2076778823 @default.
• W2026138148 cites W2082541602 @default.
• W2026138148 cites W2084000999 @default.
• W2026138148 cites W2090722308 @default.
• W2026138148 cites W2108396632 @default.
• W2026138148 cites W2121930130 @default.
• W2026138148 cites W2127833220 @default.
• W2026138148 cites W2130795028 @default.
• W2026138148 cites W2133896684 @default.
• W2026138148 cites W2155536801 @default.
• W2026138148 cites W2156121263 @default.
• W2026138148 cites W2169084547 @default.
• W2026138148 cites W2169265687 @default.
• W2026138148 cites W2211767371 @default.
• W2026138148 cites W2292008529 @default.
• W2026138148 cites W2315595592 @default.
• W2026138148 cites W4211201192 @default.
• W2026138148 doi "https://doi.org/10.1038/hr.2011.213" @default.
• W2026138148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22158110" @default.
• W2026138148 hasPublicationYear "2011" @default.
• W2026138148 type Work @default.
• W2026138148 sameAs 2026138148 @default.
• W2026138148 citedByCount "37" @default.
• W2026138148 countsByYear W20261381482012 @default.
• W2026138148 countsByYear W20261381482013 @default.
• W2026138148 countsByYear W20261381482014 @default.
• W2026138148 countsByYear W20261381482015 @default.
• W2026138148 countsByYear W20261381482016 @default.
• W2026138148 countsByYear W20261381482017 @default.
• W2026138148 countsByYear W20261381482018 @default.
• W2026138148 countsByYear W20261381482019 @default.
• W2026138148 countsByYear W20261381482020 @default.
• W2026138148 countsByYear W20261381482021 @default.
• W2026138148 countsByYear W20261381482022 @default.
• W2026138148 countsByYear W20261381482023 @default.
• W2026138148 crossrefType "journal-article" @default.
• W2026138148 hasAuthorship W2026138148A5006602845 @default.
• W2026138148 hasAuthorship W2026138148A5009941415 @default.
• W2026138148 hasAuthorship W2026138148A5020440584 @default.
• W2026138148 hasAuthorship W2026138148A5021926190 @default.
• W2026138148 hasAuthorship W2026138148A5056854844 @default.
• W2026138148 hasAuthorship W2026138148A5060781017 @default.
• W2026138148 hasAuthorship W2026138148A5071033298 @default.
• W2026138148 hasAuthorship W2026138148A5071801392 @default.
• W2026138148 hasAuthorship W2026138148A5080247489 @default.
• W2026138148 hasAuthorship W2026138148A5081613438 @default.
• W2026138148 hasBestOaLocation W20261381481 @default.
• W2026138148 hasConcept C104317684 @default.
• W2026138148 hasConcept C126322002 @default.
• W2026138148 hasConcept C127413603 @default.
• W2026138148 hasConcept C134018914 @default.
• W2026138148 hasConcept C135763542 @default.
• W2026138148 hasConcept C156957248 @default.
• W2026138148 hasConcept C158086472 @default.
• W2026138148 hasConcept C180754005 @default.
• W2026138148 hasConcept C203663253 @default.
• W2026138148 hasConcept C2776151105 @default.
• W2026138148 hasConcept C2777097880 @default.
• W2026138148 hasConcept C2778760513 @default.
• W2026138148 hasConcept C2778979269 @default.
• W2026138148 hasConcept C2780221984 @default.
• W2026138148 hasConcept C2780645631 @default.
• W2026138148 hasConcept C44249647 @default.
• W2026138148 hasConcept C54355233 @default.
• W2026138148 hasConcept C71924100 @default.
• W2026138148 hasConcept C78519656 @default.

• next