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• W2026170500 abstract "LPS and IL-2 play an essential role in the generation of the immune response in diverse eukaryotic species, as they provoke the activation of several pathways of signal transduction in macrophages. Among the kinases related to these pathways, PKA and the PKCs are some of the most important. In the haemolymph of the marine mussel Mytilus galloprovincialis Lmk, the cells responsible for the defence reactions are the haemocytes. These act as active phagocytes, and are able also to secrete humoral factors. The effect of the stimulation of the haemocytes with either LPS or IL-2 on the expression of both a Ca(2+)-independent PKC (p105) and a regulatory subunit (RII) of PKA found in mussel tissues are studied in this work. Also, the effect of inhibitors specific for these kinases on their expression and on their release of catecholamines is reported." @default.
• W2026170500 created "2016-06-24" @default.
• W2026170500 creator A5043313557 @default.
• W2026170500 creator A5044114270 @default.
• W2026170500 creator A5044581487 @default.
• W2026170500 date "2004-05-01" @default.
• W2026170500 modified "2023-09-27" @default.
• W2026170500 title "Implication of PKA and PKC in the activation of the haemocytes of Mytilus galloprovincialis Lmk. by LPS and IL-2" @default.
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• W2026170500 doi "https://doi.org/10.1016/j.molimm.2004.02.002" @default.
• W2026170500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15140574" @default.
• W2026170500 hasPublicationYear "2004" @default.
• W2026170500 type Work @default.
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• W2026170500 citedByCount "26" @default.

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