FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026173407> ?p ?o ?g. }

• W2026173407 endingPage "143" @default.
• W2026173407 startingPage "135" @default.
• W2026173407 abstract "Evidence is presented that rat liver microsomal fatty acid chain elongation synthesis and desaturation, as well as acetyl-CoA carboxylase and fatty acid synthetase, are strongly influenced by thyroid hormone level. Conversely, the fatty acid chain elongation system in mitochondria, unlike the oxidative capacity of palmitate, NADH, succinate and malate, does not seem significantly affected by the thyrotoxic state. In triiodothyronine-induced or thyroxine-induced hyperthyroidism, rat liver acetyl-CoA carboxylase, fatty acid synthetase and microsomal chain elongation and desaturation reactions are not greatly affected after the first 10 days of treatment, while after longer intervals a respective increase in these activities is shown of up to 87, 116 and 65% after 22 days. In propylthiouracil-induced hypothyroidism, all the above synthetic activities are strongly reduced immediately after three days of drug administration and diminished no further following longer periods. Although the pattern of synthesized fatty acids in the thyrotoxic state is similar to that obtained from normal subcellular rat fractions, the esterification process of fatty acids in microsomal lipids appears to be slightly inhibited in hypothyroid rats and increased following triiodothyronine or thyroxine administration. Finally, a reduction in the hepatic cyclic AMP level of about 41% is reported after 19 days of triiodothyronine-administration to rats. On the basis of the observed insensitivity of the mitochondrial fatty acid chain elongation system to the thyrotoxic state, a tentative interpretation of its role in the hepatic cell is postulated." @default.
• W2026173407 created "2016-06-24" @default.
• W2026173407 creator A5005779628 @default.
• W2026173407 creator A5013056560 @default.
• W2026173407 creator A5027596459 @default.
• W2026173407 date "1976-12-01" @default.
• W2026173407 modified "2023-09-23" @default.
• W2026173407 title "Effect of Thyroid Hormones on Microsomal Fatty Acid Chain Elongation Synthesis in Rat Liver" @default.
• W2026173407 cites W1485064320 @default.
• W2026173407 cites W1506043065 @default.
• W2026173407 cites W1545748748 @default.
• W2026173407 cites W1554968189 @default.
• W2026173407 cites W1577233937 @default.
• W2026173407 cites W1581581849 @default.
• W2026173407 cites W1587835570 @default.
• W2026173407 cites W1603135741 @default.
• W2026173407 cites W1857443128 @default.
• W2026173407 cites W1868230021 @default.
• W2026173407 cites W188363953 @default.
• W2026173407 cites W1969561594 @default.
• W2026173407 cites W1981291152 @default.
• W2026173407 cites W1984244554 @default.
• W2026173407 cites W1990268190 @default.
• W2026173407 cites W1990595964 @default.
• W2026173407 cites W1996466550 @default.
• W2026173407 cites W2004284683 @default.
• W2026173407 cites W2008959122 @default.
• W2026173407 cites W2013944686 @default.
• W2026173407 cites W2039581459 @default.
• W2026173407 cites W2040747762 @default.
• W2026173407 cites W2043320564 @default.
• W2026173407 cites W2049942469 @default.
• W2026173407 cites W2053475904 @default.
• W2026173407 cites W2054313217 @default.
• W2026173407 cites W2058272150 @default.
• W2026173407 cites W2065187755 @default.
• W2026173407 cites W2068759221 @default.
• W2026173407 cites W2081452181 @default.
• W2026173407 cites W2082261474 @default.
• W2026173407 cites W2091929573 @default.
• W2026173407 cites W2122620532 @default.
• W2026173407 cites W2308235937 @default.
• W2026173407 cites W2410488314 @default.
• W2026173407 cites W4300832549 @default.
• W2026173407 cites W2893951330 @default.
• W2026173407 doi "https://doi.org/10.1111/j.1432-1033.1976.tb11099.x" @default.
• W2026173407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12955" @default.
• W2026173407 hasPublicationYear "1976" @default.
• W2026173407 type Work @default.
• W2026173407 sameAs 2026173407 @default.
• W2026173407 citedByCount "51" @default.
• W2026173407 countsByYear W20261734072012 @default.
• W2026173407 countsByYear W20261734072013 @default.
• W2026173407 countsByYear W20261734072014 @default.
• W2026173407 crossrefType "journal-article" @default.
• W2026173407 hasAuthorship W2026173407A5005779628 @default.
• W2026173407 hasAuthorship W2026173407A5013056560 @default.
• W2026173407 hasAuthorship W2026173407A5027596459 @default.
• W2026173407 hasBestOaLocation W20261734071 @default.
• W2026173407 hasConcept C126322002 @default.
• W2026173407 hasConcept C134018914 @default.
• W2026173407 hasConcept C181199279 @default.
• W2026173407 hasConcept C185592680 @default.
• W2026173407 hasConcept C2775960720 @default.
• W2026173407 hasConcept C2776941171 @default.
• W2026173407 hasConcept C2778288131 @default.
• W2026173407 hasConcept C526584372 @default.
• W2026173407 hasConcept C543025807 @default.
• W2026173407 hasConcept C55493867 @default.
• W2026173407 hasConcept C71315377 @default.
• W2026173407 hasConcept C71924100 @default.
• W2026173407 hasConcept C86803240 @default.
• W2026173407 hasConcept C87644729 @default.
• W2026173407 hasConceptScore W2026173407C126322002 @default.
• W2026173407 hasConceptScore W2026173407C134018914 @default.
• W2026173407 hasConceptScore W2026173407C181199279 @default.
• W2026173407 hasConceptScore W2026173407C185592680 @default.
• W2026173407 hasConceptScore W2026173407C2775960720 @default.
• W2026173407 hasConceptScore W2026173407C2776941171 @default.
• W2026173407 hasConceptScore W2026173407C2778288131 @default.
• W2026173407 hasConceptScore W2026173407C526584372 @default.
• W2026173407 hasConceptScore W2026173407C543025807 @default.
• W2026173407 hasConceptScore W2026173407C55493867 @default.
• W2026173407 hasConceptScore W2026173407C71315377 @default.
• W2026173407 hasConceptScore W2026173407C71924100 @default.
• W2026173407 hasConceptScore W2026173407C86803240 @default.
• W2026173407 hasConceptScore W2026173407C87644729 @default.
• W2026173407 hasIssue "1" @default.
• W2026173407 hasLocation W20261734071 @default.
• W2026173407 hasLocation W20261734072 @default.
• W2026173407 hasOpenAccess W2026173407 @default.
• W2026173407 hasPrimaryLocation W20261734071 @default.
• W2026173407 hasRelatedWork W1986172466 @default.
• W2026173407 hasRelatedWork W2026173407 @default.
• W2026173407 hasRelatedWork W2027938488 @default.
• W2026173407 hasRelatedWork W2050375916 @default.
• W2026173407 hasRelatedWork W2069420617 @default.
• W2026173407 hasRelatedWork W2076804102 @default.

• next