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• W2026176961 abstract "In this review, we examine the functions of the striatum and the evidence that this brain region may be compromised in antisocial individuals. The striatum is involved in the processing of reward-related information and is thus important in reward-based learning. We review evidence from a growing number of brain imaging studies that have identified differences in the structure or functioning of the striatum either in antisocial groups or in relation to personality traits that are associated with antisocial behavior such as impulsivity and novelty seeking. Evidence from structural imaging studies suggests that the volume of the striatum is increased in antisocial populations, although evidence of localization to specific subregions is inconsistent. Functional imaging studies, which similarly tend to find increased functioning in the striatum, suggest that the striatum is not necessarily hypersensitive to the receipt of reward in antisocial individuals but instead may not be appropriately processing the absence of a reward, resulting in continuous responding to a stimulus that is no longer rewarding. This may impair the ability of individuals to flexibly respond to the environment, thus contributing to impulsivity and antisocial behavior. We conclude by discussing genetic and environmental factors that may affect the development of the striatum." @default.
• W2026176961 created "2016-06-24" @default.
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• W2026176961 date "2012-11-01" @default.
• W2026176961 modified "2023-09-23" @default.
• W2026176961 title "The Potential Role of the Striatum in Antisocial Behavior and Psychopathy" @default.
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• W2026176961 doi "https://doi.org/10.1016/j.biopsych.2012.04.027" @default.
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