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- W2026225426 abstract "Peroxiredoxins are abundant cellular antioxidant proteins that help to control intracellular peroxide levels. These proteins may also function, in part, through an evolved sensitivity of some peroxiredoxins towards peroxide-mediated inactivation in hydrogen peroxide signaling in eukaryotes. This review summarizes recent progress in our understanding of the catalytic and regulatory mechanisms of 'typical 2-Cys' peroxiredoxins and of the biological roles played by these important enzymes in oxidative stress and nonstress-related cellular signaling. New evidence suggests localized peroxide buildup plays a role in nonstress-related signaling." @default.
- W2026225426 created "2016-06-24" @default.
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- W2026225426 date "2009-05-01" @default.
- W2026225426 modified "2023-10-02" @default.
- W2026225426 title "Typical 2-Cys peroxiredoxins - structures, mechanisms and functions" @default.
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- W2026225426 doi "https://doi.org/10.1111/j.1742-4658.2009.06985.x" @default.
- W2026225426 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2747500" @default.
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