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- W2026229007 abstract "High ammonia levels in mammalian tissues, especially blood (as well as in urine), are toxic, causing severe metabolic disorders. The underlying pathogenic principles are for the most part poorly understood. In this review we discuss 1) possible mechanisms of ammonia toxicity, 2) general mechanisms of bacterial ammonia production and 3) Klebsiella virulence. Special reference is made to possible effects of nitrogen fixation, ureolysis, proteolysis and amino acid ammonification." @default.
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- W2026229007 date "1998-10-01" @default.
- W2026229007 modified "2023-09-27" @default.
- W2026229007 title "Does ammonia production by Klebsiella contribute to pathogenesis?" @default.
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- W2026229007 doi "https://doi.org/10.1016/s0020-2452(99)80006-2" @default.
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