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• W2026232914 abstract "A kinetic study of CO(2) hydration was carried out using the water-soluble zinc model complex with water-soluble nitrilotris(2-benzimidazolylmethyl-6-sulfonate) L1S, [L1SZn(OH(2))](-), mimicking the active site of carbonic anhydrase, in the presence and absence of anion inhibitors NCS(-) and Cl(-). The obtained rate constants k(cat) for CO(2) hydration were 5.9x10(2), 1. 7x10(3), and 3.1x10(3) M(-1) s(-1) at 5, 10, and 15 degrees C, respectively: the k(cat)=ca. 10(4) M(-1) s(-1) extrapolated towards 25 degrees C has been the largest among the reported k(cat) using zinc model complexes for carbonic anhydrase. It was also revealed that NCS(-), Cl(-) and acetazolamide play a role of inhibitors by the decrease of k(cat): 7x10(2) and 2x10(3) M(-1) s(-1) for NCS(-) and Cl(-) at 15 degrees C, respectively. The sequence of their magnitudes in k(cat) is Cl(-) approximately acetazolamide>NCS(-), where the sequence Cl(-)>NCS(-) is confirmed for native carbonic anhydrase. The difference of k(cat) or k(obs) between NCS(-) and Cl(-) resulted from that between the stability constants K(st)=2x10(3) for [L1SZn(NCS)](2-) and 1x10(2) M(-1) for [L1SZnCl](2-) in D(2)O: for water-insoluble tris(2-benzimidazolylmethyl)amine L1, K(st)=1.8x10(4) for [L1Zn(NCS)](2-) and 1.5x10(3) M(-1) for [L1ZnCl](2-)in CD(3)CN/D(2)O (50% v/v). The crystal structure of anion-binding zinc model complexes [L1Zn(OH(2))](0.5)[L1ZnCl](0.5) (ClO(4))(1.5) 1(0.5)2(0.5)(ClO(4))(1.5) was revealed by X-ray crystallography. The geometry around Zn(2+) in 1 and 2 was tetrahedrally coordinated by three benzimidazolyl nitrogen atoms and one oxygen atom of H(2)O, or Cl(-)." @default.
• W2026232914 created "2016-06-24" @default.
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• W2026232914 date "2002-04-01" @default.
• W2026232914 modified "2023-09-24" @default.
• W2026232914 title "Kinetic study of catalytic CO2 hydration by water-soluble model compound of carbonic anhydrase and anion inhibition effect on CO2 hydration" @default.
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• W2026232914 cites W1605257743 @default.
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• W2026232914 cites W1968628941 @default.
• W2026232914 cites W1968980421 @default.
• W2026232914 cites W1971678252 @default.
• W2026232914 cites W1971927987 @default.
• W2026232914 cites W1972429431 @default.
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• W2026232914 cites W1982941878 @default.
• W2026232914 cites W1983219972 @default.
• W2026232914 cites W1983933989 @default.
• W2026232914 cites W1986894327 @default.
• W2026232914 cites W1989221403 @default.
• W2026232914 cites W1989392022 @default.
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• W2026232914 cites W2007934301 @default.
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• W2026232914 cites W2024046233 @default.
• W2026232914 cites W2025593014 @default.
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• W2026232914 cites W2045036164 @default.
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• W2026232914 cites W2067771524 @default.
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• W2026232914 doi "https://doi.org/10.1016/s0162-0134(01)00419-6" @default.
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