Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026261607> ?p ?o ?g. }
- W2026261607 endingPage "169" @default.
- W2026261607 startingPage "162" @default.
- W2026261607 abstract "Scrapie and CWD are horizontally transmissible, and the environment likely serves as a stable reservoir of infectious prions, facilitating a sustained incidence of CWD in free-ranging cervid populations and complicating efforts to eliminate disease in captive herds. Prions will enter the environment through mortalities and/or shedding from live hosts. Unfortunately, a sensitive detection method to identify prion contamination in environmental samples has not yet been developed. An environmentally-relevant prion model must be used in experimental studies. Changes in PrPSc structure upon environmental exposure may be as significant as changes in PrPSc quantity, since the structure can directly affect infectivity and disease pathology. Prions strongly bind to soil and remain infectious. Conformational changes upon adsorption, competitive sorption, and potential for desorption and transport all warrant further investigation. Mitigation of contaminated carcasses or soil might be accomplished with enzyme treatments or composting in lieu of incineration." @default.
- W2026261607 created "2016-06-24" @default.
- W2026261607 creator A5058589583 @default.
- W2026261607 creator A5072948807 @default.
- W2026261607 creator A5080657235 @default.
- W2026261607 date "2008-10-01" @default.
- W2026261607 modified "2023-10-11" @default.
- W2026261607 title "Prions in the environment" @default.
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