Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026285963> ?p ?o ?g. }
- W2026285963 endingPage "288" @default.
- W2026285963 startingPage "276" @default.
- W2026285963 abstract "In this study a novel kind of porous poly(l-glutamic acid) (PLGA)/chitosan polyelectrolyte complex (PEC) microsphere was developed through electrostatic interaction between PLGA and chitosan. By adjusting the formula parameters chitosan microspheres with an average pore size of 47.5 ± 5.4 μm were first developed at a concentration of 2 wt.% and freeze temperature of −20 °C. For self-assembly of the PEC microspheres porous chitosan microspheres were then incubated in PLGA solution at 37 °C. Due to electrostatic interaction a large amount of PLGA (110.3 μg mg−1) was homogeneously absorbed within the chitosan microspheres. The developed PEC microspheres retained their original size, pore diameters and interconnected porous structure. Fourier transform infrared spectroscopy, thermal gravimetric analysis and zeta potential analysis revealed that the PEC microspheres were successfully prepared through electrostatic interaction. Compared with microspheres fabricated from chitosan, the porous PEC microspheres were shown to efficiently promote chondrocyte attachment and proliferation. After injection subcutaneously for 8 weeks PEC microspheres loaded with chondrocytes were found to produce significant more cartilaginous matrix than chitosan microspheres. These results indicate that these novel fabricated porous PLGA/chitosan PEC microspheres could be used as injectable cell carriers for cartilage tissue engineering." @default.
- W2026285963 created "2016-06-24" @default.
- W2026285963 creator A5014310116 @default.
- W2026285963 creator A5019434673 @default.
- W2026285963 creator A5052633287 @default.
- W2026285963 creator A5064090543 @default.
- W2026285963 creator A5066444914 @default.
- W2026285963 creator A5071172951 @default.
- W2026285963 creator A5076007929 @default.
- W2026285963 date "2014-01-01" @default.
- W2026285963 modified "2023-10-02" @default.
- W2026285963 title "Poly(l-glutamic acid)/chitosan polyelectrolyte complex porous microspheres as cell microcarriers for cartilage regeneration" @default.
- W2026285963 cites W1834480331 @default.
- W2026285963 cites W1978643345 @default.
- W2026285963 cites W1982208819 @default.
- W2026285963 cites W1982498935 @default.
- W2026285963 cites W1984734563 @default.
- W2026285963 cites W1986689667 @default.
- W2026285963 cites W1991499664 @default.
- W2026285963 cites W1995237030 @default.
- W2026285963 cites W2000370155 @default.
- W2026285963 cites W2002794619 @default.
- W2026285963 cites W2007541230 @default.
- W2026285963 cites W2007953867 @default.
- W2026285963 cites W2008850772 @default.
- W2026285963 cites W2016211943 @default.
- W2026285963 cites W2024299064 @default.
- W2026285963 cites W2025188750 @default.
- W2026285963 cites W2029071943 @default.
- W2026285963 cites W2033602995 @default.
- W2026285963 cites W2040242857 @default.
- W2026285963 cites W2043430639 @default.
- W2026285963 cites W2044140318 @default.
- W2026285963 cites W2052987601 @default.
- W2026285963 cites W2055476008 @default.
- W2026285963 cites W2055869254 @default.
- W2026285963 cites W2056966258 @default.
- W2026285963 cites W2059608826 @default.
- W2026285963 cites W2064921731 @default.
- W2026285963 cites W2074794805 @default.
- W2026285963 cites W2075770284 @default.
- W2026285963 cites W2077172451 @default.
- W2026285963 cites W2077238178 @default.
- W2026285963 cites W2081493792 @default.
- W2026285963 cites W2087398726 @default.
- W2026285963 cites W2089775657 @default.
- W2026285963 cites W2095071878 @default.
- W2026285963 cites W2097059359 @default.
- W2026285963 cites W2113874846 @default.
- W2026285963 cites W2129004006 @default.
- W2026285963 cites W2131945662 @default.
- W2026285963 cites W2139077617 @default.
- W2026285963 cites W2143252344 @default.
- W2026285963 cites W2158587075 @default.
- W2026285963 cites W2168745374 @default.
- W2026285963 cites W2256998456 @default.
- W2026285963 doi "https://doi.org/10.1016/j.actbio.2013.09.002" @default.
- W2026285963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24025620" @default.
- W2026285963 hasPublicationYear "2014" @default.
- W2026285963 type Work @default.
- W2026285963 sameAs 2026285963 @default.
- W2026285963 citedByCount "108" @default.
- W2026285963 countsByYear W20262859632014 @default.
- W2026285963 countsByYear W20262859632015 @default.
- W2026285963 countsByYear W20262859632016 @default.
- W2026285963 countsByYear W20262859632017 @default.
- W2026285963 countsByYear W20262859632018 @default.
- W2026285963 countsByYear W20262859632019 @default.
- W2026285963 countsByYear W20262859632020 @default.
- W2026285963 countsByYear W20262859632021 @default.
- W2026285963 countsByYear W20262859632022 @default.
- W2026285963 countsByYear W20262859632023 @default.
- W2026285963 crossrefType "journal-article" @default.
- W2026285963 hasAuthorship W2026285963A5014310116 @default.
- W2026285963 hasAuthorship W2026285963A5019434673 @default.
- W2026285963 hasAuthorship W2026285963A5052633287 @default.
- W2026285963 hasAuthorship W2026285963A5064090543 @default.
- W2026285963 hasAuthorship W2026285963A5066444914 @default.
- W2026285963 hasAuthorship W2026285963A5071172951 @default.
- W2026285963 hasAuthorship W2026285963A5076007929 @default.
- W2026285963 hasConcept C127413603 @default.
- W2026285963 hasConcept C1491633281 @default.
- W2026285963 hasConcept C153356533 @default.
- W2026285963 hasConcept C155672457 @default.
- W2026285963 hasConcept C159985019 @default.
- W2026285963 hasConcept C171250308 @default.
- W2026285963 hasConcept C176999471 @default.
- W2026285963 hasConcept C185592680 @default.
- W2026285963 hasConcept C188027245 @default.
- W2026285963 hasConcept C192562407 @default.
- W2026285963 hasConcept C2779732960 @default.
- W2026285963 hasConcept C2780165375 @default.
- W2026285963 hasConcept C42360764 @default.
- W2026285963 hasConcept C521977710 @default.
- W2026285963 hasConcept C55493867 @default.
- W2026285963 hasConcept C86181022 @default.
- W2026285963 hasConceptScore W2026285963C127413603 @default.
- W2026285963 hasConceptScore W2026285963C1491633281 @default.