Matches in SemOpenAlex for { <https://semopenalex.org/work/W2026347977> ?p ?o ?g. }
- W2026347977 endingPage "2741" @default.
- W2026347977 startingPage "2731" @default.
- W2026347977 abstract "Abstract FoxC1 is an important transcription factor in vertebrate development since its mutation in humans results in Axenfeld‐Rieger syndrome. In the mouse, disturbance of its function causes congenital hydrocephalus and abnormalities in the development of various mesodermal derivatives. In this report, we provide one mechanistic basis for the requirement for FoxC1 in vertebrate development. We find that, in Xenopus laevis embryos, FoxC1 expression is regulated by the maternal T‐box transcription factor VegT, via the nodal sub‐family of TGFβ signaling transducers. We show that at the late neurula to early tailbud stage, FoxC1 depletion causes the down‐regulation of adhesion molecules, EP and E cadherin, as well as members of the Ephrin/EphR signaling families in the mesoderm germ layer resulting in the loss of adhesion and apoptosis of mesodermal cells. Developmental Dynamics 236:2731–2741, 2007. © 2007 Wiley‐Liss, Inc." @default.
- W2026347977 created "2016-06-24" @default.
- W2026347977 creator A5010696699 @default.
- W2026347977 creator A5014530897 @default.
- W2026347977 creator A5015563057 @default.
- W2026347977 creator A5018827870 @default.
- W2026347977 creator A5020693147 @default.
- W2026347977 creator A5070199661 @default.
- W2026347977 creator A5089654223 @default.
- W2026347977 date "2007-08-17" @default.
- W2026347977 modified "2023-10-15" @default.
- W2026347977 title "The role of FoxC1 in earlyXenopus development" @default.
- W2026347977 cites W1506300014 @default.
- W2026347977 cites W1875292783 @default.
- W2026347977 cites W1951991875 @default.
- W2026347977 cites W1964990042 @default.
- W2026347977 cites W1976037175 @default.
- W2026347977 cites W1982550220 @default.
- W2026347977 cites W2002191689 @default.
- W2026347977 cites W2008241074 @default.
- W2026347977 cites W2011237068 @default.
- W2026347977 cites W2011335970 @default.
- W2026347977 cites W2011719393 @default.
- W2026347977 cites W2012672654 @default.
- W2026347977 cites W2017629670 @default.
- W2026347977 cites W2020581747 @default.
- W2026347977 cites W2024086907 @default.
- W2026347977 cites W2025672028 @default.
- W2026347977 cites W2036490184 @default.
- W2026347977 cites W2037407502 @default.
- W2026347977 cites W2049540084 @default.
- W2026347977 cites W2065589829 @default.
- W2026347977 cites W2068224181 @default.
- W2026347977 cites W2069312900 @default.
- W2026347977 cites W2070326422 @default.
- W2026347977 cites W2076541146 @default.
- W2026347977 cites W2078808825 @default.
- W2026347977 cites W2079329077 @default.
- W2026347977 cites W2081971711 @default.
- W2026347977 cites W2082365758 @default.
- W2026347977 cites W2088852482 @default.
- W2026347977 cites W2099173483 @default.
- W2026347977 cites W2139043462 @default.
- W2026347977 cites W2140108163 @default.
- W2026347977 cites W2147136456 @default.
- W2026347977 cites W2148282826 @default.
- W2026347977 cites W2150024705 @default.
- W2026347977 cites W2163954268 @default.
- W2026347977 cites W2186646946 @default.
- W2026347977 cites W2208796000 @default.
- W2026347977 cites W2300202108 @default.
- W2026347977 cites W317124068 @default.
- W2026347977 doi "https://doi.org/10.1002/dvdy.21240" @default.
- W2026347977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17705306" @default.
- W2026347977 hasPublicationYear "2007" @default.
- W2026347977 type Work @default.
- W2026347977 sameAs 2026347977 @default.
- W2026347977 citedByCount "16" @default.
- W2026347977 countsByYear W20263479772012 @default.
- W2026347977 countsByYear W20263479772014 @default.
- W2026347977 countsByYear W20263479772015 @default.
- W2026347977 countsByYear W20263479772016 @default.
- W2026347977 countsByYear W20263479772018 @default.
- W2026347977 countsByYear W20263479772019 @default.
- W2026347977 countsByYear W20263479772021 @default.
- W2026347977 crossrefType "journal-article" @default.
- W2026347977 hasAuthorship W2026347977A5010696699 @default.
- W2026347977 hasAuthorship W2026347977A5014530897 @default.
- W2026347977 hasAuthorship W2026347977A5015563057 @default.
- W2026347977 hasAuthorship W2026347977A5018827870 @default.
- W2026347977 hasAuthorship W2026347977A5020693147 @default.
- W2026347977 hasAuthorship W2026347977A5070199661 @default.
- W2026347977 hasAuthorship W2026347977A5089654223 @default.
- W2026347977 hasBestOaLocation W20263479771 @default.
- W2026347977 hasConcept C104317684 @default.
- W2026347977 hasConcept C107459253 @default.
- W2026347977 hasConcept C129536746 @default.
- W2026347977 hasConcept C145103041 @default.
- W2026347977 hasConcept C168609215 @default.
- W2026347977 hasConcept C18155467 @default.
- W2026347977 hasConcept C196843134 @default.
- W2026347977 hasConcept C205583638 @default.
- W2026347977 hasConcept C2779535977 @default.
- W2026347977 hasConcept C2780915607 @default.
- W2026347977 hasConcept C41623484 @default.
- W2026347977 hasConcept C54355233 @default.
- W2026347977 hasConcept C83330619 @default.
- W2026347977 hasConcept C86339819 @default.
- W2026347977 hasConcept C86803240 @default.
- W2026347977 hasConcept C87073359 @default.
- W2026347977 hasConcept C95444343 @default.
- W2026347977 hasConceptScore W2026347977C104317684 @default.
- W2026347977 hasConceptScore W2026347977C107459253 @default.
- W2026347977 hasConceptScore W2026347977C129536746 @default.
- W2026347977 hasConceptScore W2026347977C145103041 @default.
- W2026347977 hasConceptScore W2026347977C168609215 @default.
- W2026347977 hasConceptScore W2026347977C18155467 @default.
- W2026347977 hasConceptScore W2026347977C196843134 @default.